TIFURAC SODIUM

Details

Stereochemistry	ACHIRAL
Molecular Formula	C18H13O4S.Na.H2O
Molecular Weight	366.363
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O.[Na+].CSC1=CC=C(C=C1)C(=O)C2=CC(CC([O-])=O)=CC3=C2OC=C3

InChI

InChIKey=DCTVJZGYZTWBLO-UHFFFAOYSA-M

InChI=1S/C18H14O4S.Na.H2O/c1-23-14-4-2-12(3-5-14)17(21)15-9-11(10-16(19)20)8-13-6-7-22-18(13)15;;/h2-9H,10H2,1H3,(H,19,20);;1H2/q;+1;/p-1

HIDE SMILES / InChI

Molecular Formula	C18H14O4S
Molecular Weight	326.366
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	H2O
Molecular Weight	18.0153
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3491210 | https://www.ncbi.nlm.nih.gov/pubmed/2608628 | https://www.ncbi.nlm.nih.gov/pubmed/3509292

Tifurac is a benzofuranacetic acid derivative patented by Syntex, Inc. as an analgesic, anti-inflammatory, and antipyretic agent. In preclinical models, Tifurac can exert anti-inflammatory and analgesic activity in rat paw edema assay and mouse writhing assay.

Originator

Approval Year

PubMed

Title	Date	PubMed
Analgetic and antiinflammatory 7-aroylbenzofuran-5-ylacetic acids and 7-aroylbenzothiophene-5-ylacetic acids.	1986 Nov	3491210
Synthesis and biological evaluation of omega-(N,N,N-trialkylammonium)alkyl esters and thioesters of carboxylic acid nonsteroidal antiinflammatory agents.	1989 Oct	2608628

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 05:10:56 GMT 2023` Edited by `admin` on `Sat Dec 16 05:10:56 GMT 2023`
Record UNII	S5TJ79BX74
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TIFURAC SODIUM

Official Name

English

TIFURAC SODIUM [USAN]

Common Name

English

5-BENZOFURANACETIC ACID, 7-(4-(METHYLTHIO)BENZOYL)-, SODIUM SALT, HYDRATE

Common Name

English

RS-82917-030

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C257