Upinitatug

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 14:26:31 GMT 2023` Edited by `admin` on `Sat Dec 16 14:26:31 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	15OY7NA275
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Upinitatug

Official Name

English

Immunoglobulin G1 [de-450-lysine], anti-(human sodium-dependent phosphate transport protein 2B) (human-Mus musculus monoclonal XMT-1535 γ1-chain), disulfide with human-Mus musculus monoclonal XMT-1535 κ-chain, dimer

Common Name

English

upinitatug [INN]

Common Name

English

XMT-1535

Code

English

Immunoglobulin G1-kappa, anti-[Homo sapiens SLC34A2 (solute carrier family 34 member 2, sodium/phosphate cotransporter 2B, NaPi2b, NaPi3b)], monoclonal antibody; gamma1 heavy chain humanized (1-449) [VH (Homo sapiens IGHV1-46*01 (81.6%) -(IGHD) –IGHJ4*

Common Name

English

Upifitamab

Common Name

English

Code System Code Type Description

FDA UNII

15OY7NA275

Created by admin on Sat Dec 16 14:26:31 GMT 2023 , Edited by admin on Sat Dec 16 14:26:31 GMT 2023

PRIMARY

CAS

2254118-43-7

Created by admin on Sat Dec 16 14:26:31 GMT 2023 , Edited by admin on Sat Dec 16 14:26:31 GMT 2023

PRIMARY

INN

11344

Created by admin on Sat Dec 16 14:26:31 GMT 2023 , Edited by admin on Sat Dec 16 14:26:31 GMT 2023

PRIMARY

CAS

2135437-07-7

Created by admin on Sat Dec 16 14:26:31 GMT 2023 , Edited by admin on Sat Dec 16 14:26:31 GMT 2023

NO STRUCTURE GIVEN

NCI_THESAURUS

C147578

Created by admin on Sat Dec 16 14:26:31 GMT 2023 , Edited by admin on Sat Dec 16 14:26:31 GMT 2023

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_147	2_203
2_223	4_215
2_264	2_324
1_147	1_203
2_370	2_428
3_23	3_88
3_135	3_195
4_23	4_88
4_135	4_195
1_223	3_215
1_229	2_229
1_232	2_232
1_264	1_324
1_370	1_428

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_300
N	2_300

Related Record Type Details


					S2WV6E8K0X

SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					15OY7NA275

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL