Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C35H42N4O6.C7H17NO5 |
| Molecular Weight | 809.9448 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 6 / 6 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.C[C@](CC1=CNC2=CC=CC=C12)(NC(=O)OC3C4CC5CC(C4)CC3C5)C(=O)NC[C@H](NC(=O)CCC(O)=O)C6=CC=CC=C6
InChI
InChIKey=DEZUAGYSLSZLFO-DRGCLBCYSA-N
InChI=1S/C35H42N4O6.C7H17NO5/c1-35(18-26-19-36-28-10-6-5-9-27(26)28,39-34(44)45-32-24-14-21-13-22(16-24)17-25(32)15-21)33(43)37-20-29(23-7-3-2-4-8-23)38-30(40)11-12-31(41)42;1-8-2-4(10)6(12)7(13)5(11)3-9/h2-10,19,21-22,24-25,29,32,36H,11-18,20H2,1H3,(H,37,43)(H,38,40)(H,39,44)(H,41,42);4-13H,2-3H2,1H3/t21?,22?,24?,25?,29-,32?,35+;4-,5+,6+,7+/m00/s1
| Molecular Formula | C35H42N4O6 |
| Molecular Weight | 614.7312 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
| Molecular Formula | C7H17NO5 |
| Molecular Weight | 195.2136 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
T1/2
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
2 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/8748432/ |
3 times / day multiple, oral |
CI-988 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Pharmacological characterization of a Chinese hamster ovary cell line transfected with the human CCK-B receptor gene. | 1996-08 |
|
| The CCK-B antagonist CI988 enhances the reflex-depressive effect of morphine in axotomized rats. | 1994-02-24 |
|
| Development of a class of selective cholecystokinin type B receptor antagonists having potent anxiolytic activity. | 1990-09 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:05:49 GMT 2025
by
admin
on
Mon Mar 31 18:05:49 GMT 2025
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| Record UNII |
12A1R692BX
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| Record Status |
Validated (UNII)
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| Record Version |
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admin on Mon Mar 31 18:05:49 GMT 2025 , Edited by admin on Mon Mar 31 18:05:49 GMT 2025
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ACTIVE MOIETY |