ATLIPROFEN

Details

Stereochemistry	RACEMIC
Molecular Formula	C13H12O2S
Molecular Weight	232.298
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C(O)=O)C1=CC=C(C=C1)C2=CSC=C2

InChI

InChIKey=PFLCZHOSQMPCMN-UHFFFAOYSA-N

InChI=1S/C13H12O2S/c1-9(13(14)15)10-2-4-11(5-3-10)12-6-7-16-8-12/h2-9H,1H3,(H,14,15)

HIDE SMILES / InChI

Molecular Formula	C13H12O2S
Molecular Weight	232.298
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/9135671 | https://adisinsight.springer.com/drugs/800000964

Atliprofen (previously known as IDPH 8261), a nonsteroidal anti-inflammatory cyclooxygenase inhibitor was developed as an anti-inflammatory drug. Low toxicity and high efficacy allowed making this compound a potentially useful therapeutic agent. IDPH 8261 participated in the clinical trial phase III in India for the treatment of rheumatic disorders However, information about the further development of the drug is not available.

Originator

Approval Year

PubMed

Title	Date	PubMed
Synthesis and evaluation of S-4-(3-thienyl)phenyl-alpha-methylacetic acid.	2004 Feb 23	15013005

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:40:14 GMT 2023` Edited by `admin` on `Fri Dec 15 15:40:14 GMT 2023`
Record UNII	11YB79G1Y6
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ATLIPROFEN

Official Name

English

(±)-P-3-THIENYLHYDRATROPIC ACID

Common Name

English

BENZENEACETIC ACID, .ALPHA.-METHYL-4-(3-THIENYL)-

Systematic Name

English

atliprofen [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C257