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Details

Stereochemistry UNKNOWN
Molecular Formula C17H18N2
Molecular Weight 250.3382
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AMFETAMINIL

SMILES

CC(CC1=CC=CC=C1)NC(C#N)C2=CC=CC=C2

InChI

InChIKey=NFHVTCJKAHYEQN-UHFFFAOYSA-N
InChI=1S/C17H18N2/c1-14(12-15-8-4-2-5-9-15)19-17(13-18)16-10-6-3-7-11-16/h2-11,14,17,19H,12H2,1H3

HIDE SMILES / InChI

Molecular Formula C17H18N2
Molecular Weight 250.3382
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry MIXED
Additional Stereochemistry No
Defined Stereocenters 0 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Amphetaminil is chemically an alpha-phenyl-alpha-[(1-methyl-2-phenyl)-ethylamino]-acetonitrile (1), i.e. a derivative of alpha-aminonitrile. It was was developed in the 1970s in Germany and marketed under the brand name Aponeuron. Administration of Aponeuron proved useful in the treatment of children with hyperkinetic syndrome. The subtle and crude motorics improved, symptoms of hyperactivity disappeared and the general school performance of the child improved. Aponeuron was also used in the treatment of disorders of erectile potency, chronic schizophrenia and narcolepsy. In 1974 amphetaminil was included in the class of addictives or habit-forming drugs, although prescription of the drug is not requiring adherence to strict requirements. Nevertheless, it has largely been withdrawn from clinical use.

CNS Activity

Approval Year

PubMed

Substance Class Chemical
Record UNII
0XU0V77JVE
Record Status Validated (UNII)
Record Version