Details
Stereochemistry | UNKNOWN |
Molecular Formula | C17H18N2 |
Molecular Weight | 250.3382 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 0 / 2 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(CC1=CC=CC=C1)NC(C#N)C2=CC=CC=C2
InChI
InChIKey=NFHVTCJKAHYEQN-UHFFFAOYSA-N
InChI=1S/C17H18N2/c1-14(12-15-8-4-2-5-9-15)19-17(13-18)16-10-6-3-7-11-16/h2-11,14,17,19H,12H2,1H3
Molecular Formula | C17H18N2 |
Molecular Weight | 250.3382 |
Charge | 0 |
Count |
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Stereochemistry | MIXED |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 2 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Amphetaminil is chemically an alpha-phenyl-alpha-[(1-methyl-2-phenyl)-ethylamino]-acetonitrile (1), i.e. a derivative of alpha-aminonitrile. It was was developed in the 1970s in Germany and marketed under the brand name Aponeuron. Administration of Aponeuron proved useful in the treatment of children with hyperkinetic syndrome. The subtle and crude motorics improved, symptoms of hyperactivity disappeared and the general school performance of the child improved. Aponeuron was also used in the treatment of disorders of erectile potency, chronic schizophrenia and narcolepsy. In 1974 amphetaminil was included in the class of addictives or habit-forming drugs, although prescription of the drug is not requiring adherence to strict requirements. Nevertheless, it has largely been withdrawn from clinical use.
Approval Year
PubMed
Title | Date | PubMed |
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Toxicokinetics of amphetamines: metabolism and toxicokinetic data of designer drugs, amphetamine, methamphetamine, and their N-alkyl derivatives. | 2002 Apr |
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Precursor medications as a source of methamphetamine and/or amphetamine positive drug testing results. | 2002 May |
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[Falling sleep inopportunely: treatment of narcolepsy]. | 2008 Dec 11 |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 17:29:19 GMT 2023
by
admin
on
Sat Dec 16 17:29:19 GMT 2023
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Record UNII |
0XU0V77JVE
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Record Status |
Validated (UNII)
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Record Version |
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NCI_THESAURUS |
C47795
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m1850
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241-560-8
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100000087198
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17590-01-1
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17813
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67172
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28615
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AMPHETAMINIL
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SUB05419MIG
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C74237
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4471
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CHEMBL2104064
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DTXSID80864783
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196
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0XU0V77JVE
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Related Record | Type | Details | ||
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ACTIVE MOIETY |