Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C16H22ClNO4 |
| Molecular Weight | 327.803 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(C)C(=O)CCCOC(=O)C(C)(C)OC1=CC=C(Cl)C=C1
InChI
InChIKey=CXQGFLBVUNUQIA-UHFFFAOYSA-N
InChI=1S/C16H22ClNO4/c1-16(2,22-13-9-7-12(17)8-10-13)15(20)21-11-5-6-14(19)18(3)4/h7-10H,5-6,11H2,1-4H3
| Molecular Formula | C16H22ClNO4 |
| Molecular Weight | 327.803 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Clofibride is a hypolipaemic drug of p-chlorophenoxyisobutyric type. Clofibride hypolipaemic effects could be due, partially, to a reduction of hormono-dependent lipolysis. Clofibride decreased blood cholesterol and total lipids, increased liver weight and liver catalase content, and decreased biliary excretion of cholesterol in normolipidemic rats after a 7 day treatment.
Approval Year
Sample Use Guides
Healthy volunteers received therapeutic doses of clofibrate as 2x500 mg capsules, clofibride as 2x450 mg capsules, twice daily for ten days.
Route of Administration:
Oral
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 16:21:17 UTC 2023
by
admin
on
Sat Dec 16 16:21:17 UTC 2023
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| Record UNII |
0S9SLS3L93
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| Record Status |
Validated (UNII)
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| Record Version |
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WHO-ATC |
C10AB10
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NCI_THESAURUS |
C98150
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WHO-VATC |
QC10AB10
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0S9SLS3L93
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DTXSID1022841
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C007089
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100000084335
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C78055
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DB13849
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CHEMBL1697831
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3245
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160134
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696
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CLOFIBRIDE
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SUB06708MIG
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247-912-7
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26717-47-5
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ACTIVE MOIETY |
