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TALIGLUCERASE ALFA
0R4NLX88O4
US Approved Rx (2012)
First approved in 2012
General
Record Details
Names
13
Classification
7
Identifiers
15
Subunits
1
Disulfide Links
2
Glycosylation
4
Active Moiety
1
Characteristic Attributes
3
TALIGLUCERASE ALFA
0R4NLX88O4
US Approved Rx (2012)
First approved in 2012
General
Approval Year
2012
595
Record Details
Substance Class
Protein
Protein Sub Type
Record UNII
0R4NLX88O4
Record Status
Validated (UNII)
Record Version
19
18
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12
11
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4
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Names
13
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entries
Name
Type
Language
Name
Type
Language
TALIGLUCERASE ALFA
Official Name
English
Taliglucerase alfa [WHO-DD]
Common Name
English
TALIGLUCERASE ALFA [ORANGE BOOK]
Common Name
English
PRGCD
Code
English
TALIGLUCERASE ALFA [USAN]
Common Name
English
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1
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Classification
7
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Classification Tree
Code System
Code
Classification Tree
Code System
Code
Enzymes
VATC
OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
Enzymes
taliglucerase alfa
WHO-VATC
QA16AB11
Designated/Approved
ORPHAN DRUG
Designated/Approved
Treatment of Gaucher's disease
FDA ORPHAN DRUG
191004
Biological Agent
Pharmacologic Substance
[C1909]
Biological Agent
[C307]
Enzyme Replacement or Supplement Agent
NCI_THESAURUS
C29726
SPHINGOLIPIDOSES
EMA EPAR
DISEASES
NERVOUS SYSTEM DISEASES
CENTRAL NERVOUS SYSTEM DISEASES
BRAIN DISEASES
BRAIN DISEASES, METABOLIC
BRAIN DISEASES, METABOLIC, INBORN
LYSOSOMAL STORAGE DISEASES, NERVOUS SYSTEM
SPHINGOLIPIDOSES
GAUCHER DISEASE
EMA ASSESSMENT REPORTS
ELELYSO (REFUSED: GAUCHER DISEASE)
Established Pharmacologic Class
Established Pharmacologic Class
[EPC]
Hydrolytic Lysosomal Glucocerebroside-specific Enzyme
[EPC]
NDF-RT
N0000175820
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Identifiers
15
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entries
Code System
Code
Type
Description
Code System
Code
Type
Description
DAILYMED
0R4NLX88O4
PRIMARY
USAN
WW-100
PRIMARY
CAS
1005808-93-4
PRIMARY
RXCUI
1291609
PRIMARY
RxNorm
IUPHAR
7444
PRIMARY
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Subunits
1
Subunit 0
>SUBUNIT_0
Disulfide Links
2
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From
To
From
To
1_6
1_18
1_20
1_25
Showing 1 to 2 of 2 entries
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1
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Glycosylation
4
Glycosylation Type
PLANT
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Glycosylation Link Type
Site
Glycosylation Link Type
Site
N
1_21
N
1_61
N
1_148
N
1_272
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Active Moiety
1
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entries
Related Record
Type
Details
Related Record
Type
Details
0R4NLX88O4
TALIGLUCERASE ALFA
ACTIVE MOIETY
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Characteristic Attributes
3
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Biological Half-life
PHARMACOKINETIC
[18.9 to 28.7] minutes (average)
Molecular Formula
CHEMICAL
ESTIMATED
C2580H3903N680O727S17
MOL_WEIGHT:NUMBER(CALCULATED)
CHEMICAL
ESTIMATED 56600 Da (average)
