BIETASERPINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C39H53N3O9
Molecular Weight	707.8528
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of BIETASERPINE

Structure Search

SMILES

[H][C@]12C[C@@H](OC(=O)C3=CC(OC)=C(OC)C(OC)=C3)[C@H](OC)[C@@H](C(=O)OC)[C@@]1([H])C[C@@]4([H])N(CCC5=C4N(CCN(CC)CC)C6=CC(OC)=CC=C56)C2

InChI

InChIKey=WFTSRDISOMSAQC-ZNFOTRSXSA-N

InChI=1S/C39H53N3O9/c1-9-40(10-2)15-16-42-29-20-25(45-3)11-12-26(29)27-13-14-41-22-24-19-33(37(49-7)34(39(44)50-8)28(24)21-30(41)35(27)42)51-38(43)23-17-31(46-4)36(48-6)32(18-23)47-5/h11-12,17-18,20,24,28,30,33-34,37H,9-10,13-16,19,21-22H2,1-8H3/t24-,28+,30-,33-,34+,37+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C39H53N3O9
Molecular Weight	707.8528
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	6 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://link.springer.com/article/10.1134/S1819712416030065 | https://books.google.ru/books?id=_J2ti4EkYpkC&pg=PA629&lpg=PA629&dq=BIETASERPINE&source=bl&ots=N6jzEcAOsq&sig=ACfU3U22WDBG8wURrgeALzucBFgeLZXaGQ

Bietaserpine is a derivative of a Rauwolfia alkaloid reserpine. It was used as an antihypertensive agent and marketed in the 1960s in France and Italy. Bietaserpine is believed to act by inhibiting VMAT receptors.

Approval Year

Patents

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:29:02 UTC 2023` Edited by `admin` on `Fri Dec 15 15:29:02 UTC 2023`
Record UNII	0P5B94FVD5
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BIETASERPINE

Official Name

English

S-1210

Code

English

Methyl 1-[2-(diethylamino)ethyl]-18β-hydroxy-11,17α-dimethoxy-3β,20α-yohimban-16β-carboxylate, 3,4,5-trimethoxybenzoate (ester)

Common Name

English

NSC-369865

Code

English

bietaserpine [INN]

Common Name

English

METHYL 13-(2-(DIETHYLAMINO)ETHYL)-1,2,3,4,4A.ALPHA.,5,7,8,13,13B.BETA.,14,14A.ALPHA.-DODECAHYDRO-2.ALPHA.,11-DIMETHOXY-3.BETA.-((3,4,5-TRIMETHOXYBENZOYL)OXY)BENZ(G)INDOLO(2,3-A)QUINOLIZINE-1.BETA.-CARBOXYLATE

Common Name

English

BIETASERPINE [MART.]

Common Name

English

DL-152 FREE BASE

Code

English

Bietaserpine [WHO-DD]

Common Name

English

BIETASERPINE [MI]

Common Name

English

DL 152

Code

English

Classification Tree Code System Code

WHO-ATC

C02AA07

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

WHO-VATC

QC02AA57

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

WHO-ATC

C02LA07

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

WHO-VATC

QC02LA07

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

NCI_THESAURUS

C270

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

WHO-VATC

QC02AA07

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

WHO-ATC

C02AA57

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

Code System Code Type Description

DRUG BANK

DB13575

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

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MERCK INDEX

m588

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

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Merck Index

SMS_ID

100000085902

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

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EPA CompTox

DTXSID301018918

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

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NCI_THESAURUS

C72973

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

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NSC

369865

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

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PUBCHEM

20054848

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

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ChEMBL

CHEMBL2106414

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

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FDA UNII

0P5B94FVD5

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

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CAS

53-18-9

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

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INN

1686

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

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WIKIPEDIA

BIETASERPINE

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

PRIMARY

EVMPD

SUB05826MIG

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

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ECHA (EC/EINECS)

200-165-0

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

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DRUG CENTRAL

3687

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

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MESH

C004538

Created by admin on Fri Dec 15 15:29:02 UTC 2023 , Edited by admin on Fri Dec 15 15:29:02 UTC 2023

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Related Record Type Details


					20AY3RFI45

BIETASERPINE BITARTRATE

SALT/SOLVATE -> PARENT

Related Record Type Details


					0P5B94FVD5

ACTIVE MOIETY