BIETASERPINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Possibly Marketed Outside US

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C39H53N3O9
Molecular Weight	707.8528
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of BIETASERPINE

Structure Search

SMILES

CCN(CC)CCN1C2=C(C=CC(OC)=C2)C3=C1[C@H]4C[C@H]5[C@H](C[C@@H](OC(=O)C6=CC(OC)=C(OC)C(OC)=C6)[C@H](OC)[C@H]5C(=O)OC)CN4CC3

InChI

InChIKey=WFTSRDISOMSAQC-ZNFOTRSXSA-N

InChI=1S/C39H53N3O9/c1-9-40(10-2)15-16-42-29-20-25(45-3)11-12-26(29)27-13-14-41-22-24-19-33(37(49-7)34(39(44)50-8)28(24)21-30(41)35(27)42)51-38(43)23-17-31(46-4)36(48-6)32(18-23)47-5/h11-12,17-18,20,24,28,30,33-34,37H,9-10,13-16,19,21-22H2,1-8H3/t24-,28+,30-,33-,34+,37+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C39H53N3O9
Molecular Weight	707.8528
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	6 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://link.springer.com/article/10.1134/S1819712416030065 | https://books.google.ru/books?id=_J2ti4EkYpkC&pg=PA629&lpg=PA629&dq=BIETASERPINE&source=bl&ots=N6jzEcAOsq&sig=ACfU3U22WDBG8wURrgeALzucBFgeLZXaGQ

Bietaserpine is a derivative of a Rauwolfia alkaloid reserpine. It was used as an antihypertensive agent and marketed in the 1960s in France and Italy. Bietaserpine is believed to act by inhibiting VMAT receptors.

Approval Year

Patents

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:58:39 GMT 2025` Edited by `admin` on `Mon Mar 31 17:58:39 GMT 2025`
Record UNII	0P5B94FVD5
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

BIETASERPINE

Official Name

English

DL 152

Preferred Name

English

S-1210

Code

English

Methyl 1-[2-(diethylamino)ethyl]-18?-hydroxy-11,17?-dimethoxy-3?,20?-yohimban-16?-carboxylate, 3,4,5-trimethoxybenzoate (ester)

Common Name

English

NSC-369865

Code

English

bietaserpine [INN]

Common Name

English

METHYL 13-(2-(DIETHYLAMINO)ETHYL)-1,2,3,4,4A.ALPHA.,5,7,8,13,13B.BETA.,14,14A.ALPHA.-DODECAHYDRO-2.ALPHA.,11-DIMETHOXY-3.BETA.-((3,4,5-TRIMETHOXYBENZOYL)OXY)BENZ(G)INDOLO(2,3-A)QUINOLIZINE-1.BETA.-CARBOXYLATE

Common Name

English

BIETASERPINE [MART.]

Common Name

English

DL-152 FREE BASE

Code

English

Bietaserpine [WHO-DD]

Common Name

English

BIETASERPINE [MI]

Common Name

English

Classification Tree Code System Code

WHO-ATC

C02AA07

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

WHO-VATC

QC02AA57

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

WHO-ATC

C02LA07

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

WHO-VATC

QC02LA07

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

NCI_THESAURUS

C270

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

WHO-VATC

QC02AA07

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

WHO-ATC

C02AA57

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

Code System Code Type Description

DRUG BANK

DB13575

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

PRIMARY

MERCK INDEX

m588

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

PRIMARY

Merck Index

SMS_ID

100000085902

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

PRIMARY

EPA CompTox

DTXSID301018918

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

PRIMARY

NCI_THESAURUS

C72973

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

PRIMARY

NSC

369865

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

PRIMARY

PUBCHEM

20054848

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

PRIMARY

ChEMBL

CHEMBL2106414

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

PRIMARY

FDA UNII

0P5B94FVD5

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

PRIMARY

CAS

53-18-9

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

PRIMARY

INN

1686

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

PRIMARY

WIKIPEDIA

BIETASERPINE

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

PRIMARY

EVMPD

SUB05826MIG

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

PRIMARY

ECHA (EC/EINECS)

200-165-0

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

PRIMARY

DRUG CENTRAL

3687

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

PRIMARY

MESH

C004538

Created by admin on Mon Mar 31 17:58:39 GMT 2025 , Edited by admin on Mon Mar 31 17:58:39 GMT 2025

PRIMARY

Related Record Type Details


					20AY3RFI45

BIETASERPINE BITARTRATE

SALT/SOLVATE -> PARENT

Related Record Type Details


					0P5B94FVD5

ACTIVE MOIETY