MAGNESIUM ASCORBATE

First approved in 2009

Details

Stereochemistry	ABSOLUTE
Molecular Formula	2C6H7O6.Mg
Molecular Weight	374.5374
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Mg++].[H][C@@]1(OC(=O)C(O)=C1[O-])[C@@H](O)CO.[H][C@@]2(OC(=O)C(O)=C2[O-])[C@@H](O)CO

InChI

InChIKey=AIOKQVJVNPDJKA-ZZMNMWMASA-L

InChI=1S/2C6H8O6.Mg/c2*7-1-2(8)5-3(9)4(10)6(11)12-5;/h2*2,5,7-10H,1H2;/q;;+2/p-2/t2*2-,5+;/m00./s1

HIDE SMILES / InChI

Molecular Formula	Mg
Molecular Weight	24.305
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C6H7O6
Molecular Weight	175.1162
Charge	-1
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: DOI: 10.2903/j.efsa.2009.994
Curator's Comment: description was created based on several sources, including: http://www.xtend-life.com/information/ingredients/magnesium_ascorbate

Magnesium ascorbate is a non-acidic buffered form of Vitamin C and a source of the essential mineral Magnesium. The in vitro model system consisted of the isolated section of rat small intestine. The sources of magnesium ion (Mg2+) were magnesium chloride, magnesium sulphate, magnesium acetate, magnesium lactate, magnesium hydrocitrate and magnesium ascorbate. Magnesium ions from magnesium ascorbate were absorbed after the first 15 minutes to the highest extent of all salts, but after 120 minutes their absorption was the smallest of all. The use of magnesium ascorbate in food supplements may lead to an additional exposure to vitamin C and Magnesium.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Oxidative Stress 160 Target ID: WP1050 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16154915	Inhibitor 8297

Conditions

Condition	Modality	Targets	Highest Phase	Product
Myocardial disease 1 Sources: https://www.ncbi.nlm.nih.gov/pubmed/6231479	Preventing		Preclinical	Magnesium Ascorbate Approved Use Unknown

PubMed

Title	Date	PubMed
[CLINICAL RESEARCH ON THE SEPARATE AND COMBINED ACTION OF QUINIC ACID AND MAGNESIUM ASCORBATE IN 64 CASES OF HYPERAZOTEMIA].	1963 Jul-Aug	14050351
Morphophysiological studies in experimental myocardial stress induced by isoproterenol. Note II. The myocardioprotector effect of magnesium ascorbate.	1984 Jan-Mar	6231479
Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as used in cosmetics.	2005	16154915

Patents

Sample Use Guides

In Vivo Use Guide

1 g twice daily (70 mg/magnesium/person/day)

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:37:42 UTC 2023` Edited by `admin` on `Fri Dec 15 18:37:42 UTC 2023`
Record UNII	0N1G678593
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MAGNESIUM ASCORBATE

Official Name

English

MAGNESIUM ASCORBATE [INCI]

Common Name

English

L(+)-ASCORBIC ACID MAGNESIUM SALT

Common Name

English

ASCORBIC ACID, MAGNESIUM SALT

Common Name

English

Magnesium ascorbate [WHO-DD]

Common Name

English

VITAMIN C MAGNESIUM SALT

Common Name

English

Classification Tree Code System Code

DSLD

2918 (Number of products:35)