CYCLOBARBITAL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H16N2O3
Molecular Weight	236.267
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCC1(C(=O)NC(=O)NC1=O)C2=CCCCC2

InChI

InChIKey=WTYGAUXICFETTC-UHFFFAOYSA-N

InChI=1S/C12H16N2O3/c1-2-12(8-6-4-3-5-7-8)9(15)13-11(17)14-10(12)16/h6H,2-5,7H2,1H3,(H2,13,14,15,16,17)

HIDE SMILES / InChI

Molecular Formula	C12H16N2O3
Molecular Weight	236.267
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://books.google.ru/books?id=szDnBwAAQBAJ&printsec=frontcover&hl=ru#v=onepage&q&f=false | https://www.sdrugs.com/?c=drug&s=reladorm

Cyclobarbital (5-cyclohexenyl-5-ethyl-barbituric acid) is a short-acting barbiturate exerting sedative-hypnotic properties. Cyclobarbital is metabolized to inactive ketocyclobarbital. The convention on psychotropic substances, which was signed in Vienna in 1971, today regulates cyclobarbital as a schedule III barbiturate. Cyclobarbital is used in combination with diazepam tranquilizer (Reladorm).

Approval Year

PubMed

Title	Date	PubMed
Molecularly imprinted polymers for simultaneous determination of antiepileptics in river water samples by liquid chromatography-tandem mass spectrometry.	2009-06-19	19439306
In silico prediction of pregnane X receptor activators by machine learning approaches.	2007-01	17003167
Comparison of the percutaneous absorption of hydrophilic and lipophilic compounds in shed snake skin and human skin.	2006-04	16649549
Quantitative determination of vigabatrin and gabapentin in human serum by gas chromatography-mass spectrometry.	2005-04	15748611
Fluorescent imprinted polymers prepared with 2-acrylamidoquinoline as a signaling monomer.	2005-02-03	15673239
Key structural features of ligands for activation of human pregnane X receptor.	2004-04	15039302
Multiple hydrogen bonding-based fluorescent imprinted polymers for cyclobarbital prepared with 2,6-bis(acrylamido)pyridine.	2003-11-21	14651107
Multimodal inclusion complexes between barbiturates and 2-hydroxypropyl-beta-cyclodextrin in aqueous solution: isothermal titration microcalorimetry, (13)C NMR spectrometry, and molecular dynamics simulation.	2001-08	11536223
Induction of CYP1A2 by phenobarbital in the livers of aryl hydrocarbon-responsive and -nonresponsive mice.	1999-03	10064569

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:50:01 GMT 2025` Edited by `admin` on `Mon Mar 31 17:50:01 GMT 2025`
Record UNII	0M8A98AD9H
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CYCLOBARBITAL

Official Name

English

CICLOBARBITAL

Preferred Name

English

CYCLOBARBITONE

Common Name

English

HEXEMAL

Common Name

English

5-(1-CYCLOHEXEN-1-YL)-5-ETHYLBARBITURIC ACID

Systematic Name

English

cyclobarbital [INN]

Common Name

English

CYCLOBARBITAL [MART.]

Common Name

English

Cyclobarbital [WHO-DD]

Common Name

English

CYCLOBARBITAL [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29756