TOLGABIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C18H18Cl2N2O2
Molecular Weight	365.254
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=CC(Cl)=CC(\C(=N\CCCC(N)=O)C2=CC=C(Cl)C=C2)=C1O

InChI

InChIKey=AOAFGVWKONLQRN-OQKWZONESA-N

InChI=1S/C18H18Cl2N2O2/c1-11-9-14(20)10-15(18(11)24)17(22-8-2-3-16(21)23)12-4-6-13(19)7-5-12/h4-7,9-10,24H,2-3,8H2,1H3,(H2,21,23)/b22-17+

HIDE SMILES / InChI

Molecular Formula	C18H18Cl2N2O2
Molecular Weight	365.254
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://apps.who.int/iris/bitstream/handle/10665/67830/WHO_EDM_QSM_2003.2.pdf | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 1215, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ | (2009) Current Organic Chemistry, v.13, page 137, retrieved from: https://books.google.ru/books?id=9VlFAQAAIAAJ

Tolgabide is a gabamimetic agent. It exhibits antiepileptic, anticonvulsant and antidyskinetic activity. Tolgabide has a very similar structure and biological properties to those of progabide.

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:19:43 GMT 2023` Edited by `admin` on `Sat Dec 16 17:19:43 GMT 2023`
Record UNII	0L55QF645F
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TOLGABIDE

Official Name

English

tolgabide [INN]

Common Name

English

SL 81.0142-00

Code

English

SL-81.0142-00

Code

English

TOLGABIDE [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C264