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Details

Stereochemistry ACHIRAL
Molecular Formula C14H12N2O4S
Molecular Weight 304.321
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TIOXACIN

SMILES

CCN1C=C(C(O)=O)C(=O)C2=C1C=CC3=C2SC(=O)N3C

InChI

InChIKey=VUUPJGYIOAVFAN-UHFFFAOYSA-N
InChI=1S/C14H12N2O4S/c1-3-16-6-7(13(18)19)11(17)10-8(16)4-5-9-12(10)21-14(20)15(9)2/h4-6H,3H2,1-2H3,(H,18,19)

HIDE SMILES / InChI

Molecular Formula C14H12N2O4S
Molecular Weight 304.321
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Tioxacin is a bactericide agent. Tioxacin gives a soluble complex with aliphatic amines and had the highest activities against G(+) and G (-) bacteria, including Escherichia coli resistant to nalidixic acid and Pseudomonas aeruginosa from 98 acids of this type. Absorption studies in dogs suggested that the amine complex may have a great utility as a rapid dissolving form of tioxacin in oral administration.

Approval Year

PubMed

Substance Class Chemical
Record UNII
0K40CNM74K
Record Status Validated (UNII)
Record Version