HEXAPROPYMATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H15NO2
Molecular Weight	181.2316
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(=O)OC1(CC#C)CCCCC1

InChI

InChIKey=MIRHIEAGDGUXKL-UHFFFAOYSA-N

InChI=1S/C10H15NO2/c1-2-6-10(13-9(11)12)7-4-3-5-8-10/h1H,3-8H2,(H2,11,12)

HIDE SMILES / InChI

Molecular Formula	C10H15NO2
Molecular Weight	181.2316
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2770531 | https://www.ncbi.nlm.nih.gov/pubmed/656827

Hexapropymate, a hypnotic/sedative drug that was available without prescription in Belgium under the trade name Merinax for the treatment of insomnia. Poisoning with hexapropymate was a serious condition that required symptomatic treatment in the intensive care unit. As a result, the drug was substituted by newer agents with improved safety profiles.

Approval Year

PubMed

Title	Date	PubMed
Hexapropymate self-poisoning causes severe and long-lasting clinical symptoms.	1989-07-01	2770531
Biotransformation of hexapropymate in man. Part 2: Isolation and identification of metabolites.	1984-02	6718477
[Effects of hexapropymate on sleep in normal humans, measured with a polygraphic method].	1975-02	1099650
[5 cases of suspected hexapropymate poisoning].	1971-01-01	5092668
[Pediatric indications for a synthetic non-barbituric hypnotic: hexapropymate].	1962-12-02	14018306

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:48:16 GMT 2025` Edited by `admin` on `Mon Mar 31 17:48:16 GMT 2025`
Record UNII	0J9RN2PRJ7
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

HEXAPROPYMATE

Official Name

English

MERINAX

Preferred Name

English

HEXAPROPYMATE [MI]

Common Name

English

HEXAPROPYMATE [MART.]

Common Name

English

hexapropymate [INN]

Common Name

English

Hexapropymate [WHO-DD]

Common Name

English

NSC-169094

Code

English

1-(2-PROPYNYL)-1-CYCLOHEXANOL CARBAMATE

Systematic Name

English

Classification Tree Code System Code

WHO-VATC

QN05CM10