| Stereochemistry | ABSOLUTE |
| Molecular Formula | C6H12O7 |
| Molecular Weight | 196.1553 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)C(O)=O
InChI
InChIKey=RGHNJXZEOKUKBD-QTBDOELSSA-N
InChI=1S/C6H12O7/c7-1-2(8)3(9)4(10)5(11)6(12)13/h2-5,7-11H,1H2,(H,12,13)/t2-,3+,4-,5-/m0/s1
| Molecular Formula | C6H12O7 |
| Molecular Weight | 196.1553 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
L-Gulonic acid, a diastereomer of d-gluconic acid is the one of a metabolite in the urinate cycle, is a substrate of L-Gulonate 3-dehydrogenase (GDH). This enzyme catalyzes the NAD(+)-linked dehydrogenation of L-gulonate into dehydro-L-gulonate. L-Gulonic acid is also a metabolite of the D-glucuronic acid pathway. It was suggested, that the measurement of a spectrum of urinary D-glucuronic acid metabolites might provide a more reliable index for assessment of the induction of hepatic xenobiotic-metabolizing enzyme activities in man than the determination of urinary D-glucaric acid alone.
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
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