5-BENZYLACYCLOURIDINE

OCCOCN1C=C(CC2=CC=CC=C2)C(=O)NC1=O

InChIKey=SPJAGILXQBHHSZ-UHFFFAOYSA-N

InChI=1S/C14H16N2O4/c17-6-7-20-10-16-9-12(13(18)15-14(16)19)8-11-4-2-1-3-5-11/h1-5,9,17H,6-8,10H2,(H,15,18,19)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Modulation of uridine phosphorylase gene expression by tumor necrosis factor-alpha enhances the antiproliferative activity of the capecitabine intermediate 5'-deoxy-5-fluorouridine in breast cancer cells.	2006-04	16397116
Different effect of benzylacyclouridine on the toxic and therapeutic effects of azidothymidine in mice.	1990-12-01	2257295
Benzylacyclouridine reverses azidothymidine-induced marrow suppression without impairment of anti-human immunodeficiency virus activity.	1990-12-01	2257294
5-benzylacyclouridine and 5-benzyloxybenzylacyclouridine, potent inhibitors of uridine phosphorylase.	1982-05-15	7104017

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:59:01 GMT 2025` Edited by `admin` on `Mon Mar 31 17:59:01 GMT 2025`
Record UNII	0H851I3O9D
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

5-BENZYLACYCLOURIDINE

Common Name

English

5-BACU

Preferred Name

English

BENZYLACYCLOURIDINE

Common Name

English

2,4(1H,3H)-PYRIMIDINEDIONE, 1-((2-HYDROXYETHOXY)METHYL)-5-(PHENYLMETHYL)-

Systematic Name

English

BAU

Common Name

English

5-BENZYL-1-(2-HYDROXYETHOXYMETHYL)URACIL

Systematic Name

English

Code System Code Type Description

DRUG BANK

DB07437