BEMARINONE HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C11H12N2O3.ClH
Molecular Weight	256.686
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.COC1=C(OC)C2=C(NC(=O)N=C2C)C=C1

InChI

InChIKey=ZEHAPDWJZZTSOT-UHFFFAOYSA-N

InChI=1S/C11H12N2O3.ClH/c1-6-9-7(13-11(14)12-6)4-5-8(15-2)10(9)16-3;/h4-5H,1-3H3,(H,12,13,14);1H

HIDE SMILES / InChI

Molecular Formula	C11H12N2O3
Molecular Weight	220.2246
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://doi.org/10.1002/ddr.430120307| | https://www.ncbi.nlm.nih.gov/pubmed/3039135

Bemarinone (ORF 16600) is a positive inotropic and vasodilator agent with potential clinical utility in the management of congestive heart failure. The compound selectively and competitively inhibited cyclic AMP phosphodiesterase fraction III. However, further studies were discontinued

Originator

Approval Year

PubMed

Title	Date	PubMed
Cardiotonic agents. Synthesis and inotropic activity of a series of isoquinolin-3-ol derivatives.	1988 Jul	3385731

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:52:14 GMT 2023` Edited by `admin` on `Fri Dec 15 15:52:14 GMT 2023`
Record UNII	0GSS0O37A8
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BEMARINONE HYDROCHLORIDE

Official Name

English

5,6-Dimethyl-4-methyl-2(1H)-quinazolinone monohydrochloride

Systematic Name

English

BEMARINONE HYDROCHLORIDE [USAN]

Common Name

English

RWJ-16600

Code

English

2(1H)-QUINAZOLINONE, 5,6-DIMETHOXY-4-METHYL-, MONOHYDROCHLORIDE

Common Name

English

ORF 16600

Code

English

BEMARINONE HCL

Common Name

English

RWJ 16600

Code

English

ORF-16600

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C744