CIPROPRIDE

Details

Stereochemistry	UNKNOWN
Molecular Formula	C17H25N3O4S
Molecular Weight	367.463
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=C(C=C(C=C1)S(N)(=O)=O)C(=O)NCC2CCCN2CC3CC3

InChI

InChIKey=BTYDXWCTJDAEHA-UHFFFAOYSA-N

InChI=1S/C17H25N3O4S/c1-24-16-7-6-14(25(18,22)23)9-15(16)17(21)19-10-13-3-2-8-20(13)11-12-4-5-12/h6-7,9,12-13H,2-5,8,10-11H2,1H3,(H,19,21)(H2,18,22,23)

HIDE SMILES / InChI

Molecular Formula	C17H25N3O4S
Molecular Weight	367.463
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7197651

Cipropride is an anti-emetic drug of the substituted benzamide class. It was discovered by Synthelabo in the early 1980s. The drug acts by blocking the dopamine receptor and thus affecting the chemo-receptor trigger zone for vomiting. Clinical trials showed that cipropride was effective for the prevention of nausea and vomiting induced by cytotoxic chemotherapy agents dacarbazine and Cis-platinum. The subsequent development of the drug was not reported.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
dopamine neurotransmitter receptor activity 1 Target ID: GO:0004952 Sources: https://www.ncbi.nlm.nih.gov/pubmed/7197651	Inhibitor 8297

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:18:05 GMT 2023` Edited by `admin` on `Fri Dec 15 16:18:05 GMT 2023`
Record UNII	0D2VUO6DCN
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CIPROPRIDE

Official Name

English

N-((1-(CYCLOPROPYLMETHYL)-2-PYRROLIDINYL)METHYL)-5-SULFAMOYL-O-ANISAMIDE

Common Name

English

cipropride [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C267