PROPIZEPINE

Investigational

Details

Stereochemistry	RACEMIC
Molecular Formula	C17H20N4O
Molecular Weight	296.3669
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

CC(CN1C2=C(NC3=C(C=CC=N3)C1=O)C=CC=C2)N(C)C

InChI

InChIKey=YFLBETLXDPBWTD-UHFFFAOYSA-N

InChI=1S/C17H20N4O/c1-12(20(2)3)11-21-15-9-5-4-8-14(15)19-16-13(17(21)22)7-6-10-18-16/h4-10,12H,11H2,1-3H3,(H,18,19)

HIDE SMILES / InChI

Molecular Formula	C17H20N4O
Molecular Weight	296.3669
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description

Propizepine is a benzodiazepinone derivative patented by Laboratoires U.P.S.A. as antidepressive, antihistaminic, antianaphylactic, thymoanaleptic, antiserotonine, antispasmodic, and analgetic compound. Propizepine used in France for the treatment of depression in the 1970s.

Originator

Approval Year

PubMed

Show entries

Title	Date	PubMed
Effects of JL13, a pyridobenzoxazepine with potential atypical antipsychotic activity, in animal models for schizophrenia.	2001 Jul	11408566
Recent advances in the solid-phase combinatorial synthetic strategies for the benzodiazepine based privileged structures.	2006 Jan	16457632
Method development for a pyridobenzodiazepine library with multiple diversification points.	2008 Mar-Apr	18260649

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Patents

Substance Class	Chemical
Record UNII	09B57945V9
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PROPIZEPINE

Official Name

English

6,11-DIHYDRO-6-(2-(DIMETHYLAMINO)-2-METHYLETHYL)-5H-PYRIDO(2,3-B)(1,5)BENZODIAZEPIN-5-ONE

Systematic Name

English

PROPIEZEPINE, (±)-

Common Name

English

(±)-PROPIEZEPINE

Common Name

English

UP 106

Code

English

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Classification Tree

Code System

Code

Agent Affecting Nervous System

NCI_THESAURUS

C265

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Code System

Code

Type

Description

INN

2470

PRIMARY

FDA UNII

09B57945V9

PRIMARY

PUBCHEM

112029

PRIMARY

MESH

C003256

PRIMARY

CAS

10321-12-7

PRIMARY

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Related Record

Type

Details


					Z5MO8L6XHR

PROPIZEPINE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

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Related Record

Type

Details


					09B57945V9

PROPIZEPINE

ACTIVE MOIETY

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