Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C14H20N2O |
| Molecular Weight | 232.3214 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(N1CCCC1)C(=O)NC2=CC=CC=C2C
InChI
InChIKey=WJOQWLQQCYYQBE-UHFFFAOYSA-N
InChI=1S/C14H20N2O/c1-11-7-3-4-8-13(11)15-14(17)12(2)16-9-5-6-10-16/h3-4,7-8,12H,5-6,9-10H2,1-2H3,(H,15,17)
| Molecular Formula | C14H20N2O |
| Molecular Weight | 232.3214 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Aptocaine (Pirothesin, Pharmaceutical Manufacturing Company) is a new local anaesthetic agent, the first of note to be synthesized in Britain. It is related toprilocaine; like prilocaine, it has a low sub-cutaneous toxicity, but preliminary studies suggest that, unlike prilocaine, it does not induce methaemoglobinaemia. It has been found to produce satisfactory analgesia, of longer duration than lignocaine, by several routes, at a concentration of 3% in animals.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Identification of metabolites of aptocaine and some related compounds [proceedings]. | 1976-12 |
|
| Intradermal study of a new local anaesthetic agent aptocaine. | 1976-04 |
|
| [A new local anesthetic for dentistry: 1st study of aptocaine chlorhydrate in combination with corbadrine chlorhydrate]. | 1971-06-01 |
Patents
| Substance Class |
Chemical
Created
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admin
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Mon Mar 31 17:58:39 GMT 2025
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| Record UNII |
08K838NNTE
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| Record Status |
Validated (UNII)
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Preferred Name | English | ||
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| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C245
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08K838NNTE
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100000087165
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71695
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2644
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19281-29-9
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242-932-2
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DTXSID40864880
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C72172
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SUB05549MIG
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C012187
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CHEMBL2104078
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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ENANTIOMER -> RACEMATE | |||
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ENANTIOMER -> RACEMATE |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
