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Details

Stereochemistry ACHIRAL
Molecular Formula C5H12NO5P
Molecular Weight 197.1262
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FR-900098

SMILES

CC(=O)N(O)CCCP(O)(O)=O

InChI

InChIKey=PKMNDDZSIHLLLI-UHFFFAOYSA-N
InChI=1S/C5H12NO5P/c1-5(7)6(8)3-2-4-12(9,10)11/h8H,2-4H2,1H3,(H2,9,10,11)

HIDE SMILES / InChI

Molecular Formula C5H12NO5P
Molecular Weight 197.1262
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Targets
PubMed

PubMed

TitleDatePubMed
Synthesis and antimalarial activity of chain substituted pivaloyloxymethyl ester analogues of Fosmidomycin and FR900098.
2006 Aug 1
Molecular epidemiology of malaria in Cameroon. XXV. In vitro activity of fosmidomycin and its derivatives against fresh clinical isolates of Plasmodium falciparum and sequence analysis of 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
2007 Aug
Synthesis and antiplasmodial activity of highly active reverse analogues of the antimalarial drug candidate fosmidomycin.
2010 Oct 4
Expression, characterization and inhibition of Toxoplasma gondii 1-deoxy-D-xylulose-5-phosphate reductoisomerase.
2013 Apr 1
DXR inhibition by potent mono- and disubstituted fosmidomycin analogues.
2013 Aug 8
The effect of chain length and unsaturation on Mtb Dxr inhibition and antitubercular killing activity of FR900098 analogs.
2014 Jan 15
Patents
Substance Class Chemical
Created
by admin
on Sat Dec 16 10:58:41 GMT 2023
Edited
by admin
on Sat Dec 16 10:58:41 GMT 2023
Record UNII
0711Y106HV
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FR-900098
Common Name English
PHOSPHONIC ACID, (3-(ACETYLHYDROXYAMINO)PROPYL)-
Systematic Name English
PHOSPHONIC ACID, P-(3-(ACETYLHYDROXYAMINO)PROPYL)-
Systematic Name English
Code System Code Type Description
PUBCHEM
162204
Created by admin on Sat Dec 16 10:58:41 GMT 2023 , Edited by admin on Sat Dec 16 10:58:41 GMT 2023
PRIMARY
FDA UNII
0711Y106HV
Created by admin on Sat Dec 16 10:58:41 GMT 2023 , Edited by admin on Sat Dec 16 10:58:41 GMT 2023
PRIMARY
CAS
66508-32-5
Created by admin on Sat Dec 16 10:58:41 GMT 2023 , Edited by admin on Sat Dec 16 10:58:41 GMT 2023
PRIMARY
EPA CompTox
DTXSID50216710
Created by admin on Sat Dec 16 10:58:41 GMT 2023 , Edited by admin on Sat Dec 16 10:58:41 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY