Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C24H44O6 |
Molecular Weight | 428.6035 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 4 / 4 |
E/Z Centers | 1 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCCCCC/C(/[H])=C(/[H])\CCCCCCCC(=O)OC[C@]([H])([C@]1([H])[C@@]([H])([C@]([H])(CO1)O)O)O
InChI
InChIKey=NWGKJDSIEKMTRX-AAZCQSIUSA-N
InChI=1S/C24H44O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(27)29-19-21(26)24-23(28)20(25)18-30-24/h9-10,20-21,23-26,28H,2-8,11-19H2,1H3/b10-9-/t20-,21+,23+,24+/m0/s1
Molecular Formula | C24H44O6 |
Molecular Weight | 428.6035 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 4 / 4 |
E/Z Centers | 1 |
Optical Activity | UNSPECIFIED |
Sorbitan monooleate (Span 80) is a partial oleate ester of sorbitol and its mono- and dianhydrides. Sorbitan Monooleate is a nonionic emulsifier and surfactant and used in cosmetics and foods. It is a food additive with the E number E495. Span 80 was suitable as surfactant in the preparation of Poly(divinylbenzene) emulsion-derived (PolyHIPE) solid foam. Anionic nanoparticles based on Span 80 as low-cost, simple and efficient non-viral gene-transfection systems. Sorbitan monooleate is approved by FDA to be used as an emulsifier in polymer dispersions that are used in the clarification of cane or beet sugar juice or liquor in an amount not to exceed 7.5 percent by weight in the final polymer dispersion. The additive is used in an amount not to exceed 0.70 part per million in sugar juice and 1.4 parts per million in sugar liquor.
Approval Year
PubMed
Title | Date | PubMed |
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Self-assembly and physicochemical and rheological properties of a polysaccharide-surfactant system formed from the cationic biopolymer chitosan and nonionic sorbitan esters. | 2006 Apr 25 |
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In vitro study of lysozyme in poly(lactide-co-glycolide) microspheres with sucrose acetate isobutyrate. | 2006 Dec |
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Fluorescence and dynamic light scattering studies of niosomes-membrane mimetic systems. | 2006 Jul |
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Microemulsions of triglyceride-based oils: The effect of co-oil and salinity on phase diagrams. | 2006 Jul-Aug |
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Single dose and multiple dose studies of itraconazole nanoparticles. | 2006 Jun |
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PLGA microcapsules with novel dimpled surfaces for pulmonary delivery of DNA. | 2006 Mar 27 |
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Cationic liposomes modified with non-ionic surfactants as effective non-viral carrier for gene transfer. | 2006 May 1 |
|
Understanding the role of surfactants on the preparation of ZnS nanocrystals. | 2006 May 1 |
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Controlled release of methotrexate from w/o microemulsion and its in vitro antitumor activity. | 2007 Apr |
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Black cohosh and St. John's wort (GYNO-Plus) for climacteric symptoms. | 2007 Apr 30 |
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Process and formulation variables in the preparation of injectable and biodegradable magnetic microspheres. | 2007 Apr 4 |
|
Effect of ciprofloxacin and chloramphenicol on humoral immune response elicited by bovine albumin encapsulated in niosomes. | 2007 Aug |
|
Polymer drop breakup in microchannels. | 2007 Dec |
|
Preparation of tiny biodegradable capsules using electrocapillary emulsification. | 2007 Dec |
|
Enhancement of intragastric acid stability of a fat emulsion meal delays gastric emptying and increases cholecystokinin release and gallbladder contraction. | 2007 Jun |
|
Direct measurement of critical nucleus size in confined volumes. | 2007 Jun 19 |
|
Innovative bola-surfactant niosomes as topical delivery systems of 5-fluorouracil for the treatment of skin cancer. | 2008 Apr 2 |
|
Intermolecular interactions and morphology of aqueous polymer/surfactant mixtures containing cationic chitosan and nonionic sorbitan esters. | 2008 Aug |
|
Linker-based lecithin microemulsions for transdermal delivery of lidocaine. | 2008 Feb 12 |
|
Formulation and evaluation of flurbiprofen microemulsion. | 2008 Jan |
|
Process design applied to optimise a directly compressible powder produced via a continuous manufacturing process. | 2008 Mar |
|
Extraction of Co(II) from aqueous solution using emulsion liquid membrane. | 2008 Mar 1 |
|
Memory-improving effect of formulation-MSS by activation of hippocampal MAPK/ERK signaling pathway in rats. | 2008 Mar 31 |
|
Coprocessing via spray drying as a formulation platform to improve the compactability of various drugs. | 2008 May |
|
Fast dissolving films made of maltodextrins. | 2008 Nov |
|
Temperature-sensitive nonionic vesicles prepared from Span 80 (sorbitan monooleate). | 2008 Oct 7 |
|
The preparation of pellets containing non-ionic surfactants by extrusion/spheronization. | 2008 Sep 1 |
|
Distribution of Sorbitan Monooleate in poly(L-lactide-co-epsilon-caprolactone) nanofibers from emulsion electrospinning. | 2009 Mar 1 |
|
Solubility of ocular therapeutic agents in self-emulsifying oils. I. Self-emulsifying oils for ocular drug delivery: solubility of indomethacin, aciclovir and hydrocortisone. | 2009 Nov-Dec |
|
Structure of high internal phase aqueous-in-oil emulsions and related inverse micelle solutions. 3. Variation of surfactant. | 2009 Sep 10 |
|
Preparation and evaluation of fast-release mephenamic acid microspheres. | 2010 |
|
Effect of counter-ions and penetration enhancers on the skin permeation of flurbiprofen. | 2010 Apr |
|
In vitro and in vivo anti-tumor effects of novel Span 80 vesicles containing immobilized Eucheuma serra agglutinin. | 2010 Apr 15 |
|
Pickering emulsions stabilized by a lipophilic surfactant and hydrophilic platelike particles. | 2010 Apr 20 |
|
Vaccine development in Staphylococcus aureus: taking the biofilm phenotype into consideration. | 2010 Aug |
|
A randomised, assessor blind, parallel group comparative efficacy trial of three products for the treatment of head lice in children--melaleuca oil and lavender oil, pyrethrins and piperonyl butoxide, and a "suffocation" product. | 2010 Aug 20 |
|
The effect of component of microemulsion for transdermal delivery of nicardipine hydrochloride. | 2010 Dec |
|
Copper complexed polymer carriers for IgG adsorption. | 2010 Dec 1 |
|
Evaluation of lung tolerance of ethanol, propylene glycol, and sorbitan monooleate as solvents in medical aerosols. | 2010 Feb |
|
Study on ultrasonically assisted emulsification and recovery of copper(II) from wastewater using an emulsion liquid membrane process. | 2010 Feb |
|
Photoprotective potential of emulsions formulated with Buriti oil (Mauritia flexuosa) against UV irradiation on keratinocytes and fibroblasts cell lines. | 2010 Jan |
|
A metal-chelate affinity reverse micellar system for protein extraction. | 2010 Jan-Feb |
|
Removal of 241Am from aqueous nitrate solutions by liquid surfactant membrane containing 2-ethylhexyl phosphonic acid mono-2-ethylhexyl ester as ion carrier. | 2010 Jun |
|
Effect of surfactant concentration on transdermal lidocaine delivery with linker microemulsions. | 2010 Jun 15 |
|
Tamoxifen-encapsulated vesicular systems: cytotoxicity evaluation in human epidermal keratinocyte cell line. | 2010 Mar |
|
Studies on the evolution of ZnO morphologies in a thermohydrolysis technique and evaluation of their functional properties. | 2010 Mar 15 |
|
New approach to hydrophobic cyanine-type photosensitizer delivery using polymeric oil-cored nanocarriers: hemolytic activity, in vitro cytotoxicity and localization in cancer cells. | 2010 Mar 18 |
|
Liposomes in double-emulsion globules. | 2010 Mar 2 |
|
Evaluation of a new oil adjuvant for use in peptide-based cancer vaccination. | 2010 Oct |
|
Development and evaluation of emulsions from Carapa guianensis (Andiroba) oil. | 2010 Sep |
Substance Class |
Chemical
Created
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admin
on
Edited
Fri Jun 25 21:10:05 UTC 2021
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admin
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Fri Jun 25 21:10:05 UTC 2021
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Record UNII |
06XEA2VD56
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Validated (UNII)
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CODEX ALIMENTARIUS (GSFA) |
INS-494
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CFR |
21 CFR 173.75
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JECFA EVALUATION |
INS-494
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NCI_THESAURUS |
C83486
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SUB23477
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1363056
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215-665-4
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M10120
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1338-43-8
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C018665
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CHEMBL2107274
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1875
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06XEA2VD56
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1338-43-8
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SUB10598MIG
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5822
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9920342
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INS-494
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C75654
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