CILOBAMINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C17H23Cl2NO
Molecular Weight	328.277
Optical Activity	( + / - )
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of CILOBAMINE

Structure Search

SMILES

CC(C)N[C@@H]1C2CCC(CC2)[C@@]1(O)C3=CC=C(Cl)C(Cl)=C3

InChI

InChIKey=MQILJMOEUMZBHK-FIMMUYGNSA-N

InChI=1S/C17H23Cl2NO/c1-10(2)20-16-11-3-5-12(6-4-11)17(16,21)13-7-8-14(18)15(19)9-13/h7-12,16,20-21H,3-6H2,1-2H3/t11?,12?,16-,17-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C17H23Cl2NO
Molecular Weight	328.277
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6724198
Curator's Comment: https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20030522&CC=WO&NR=03042162A1&KC=A1

Cilobamine is a drug which acts as a norepinephrine-dopamine reuptake inhibitor (NDRI) and has stimulant and antidepressant effects.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Dose related induction of the drug metabolizing enzymes of rat liver by cilobamine.	1984-04	6724198

Patents

Patents

Sample Use Guides

In Vivo Use Guide

rat: 3, 10, 30, 100, and 300 mg/kg po for 4 days

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:20:26 GMT 2025` Edited by `admin` on `Mon Mar 31 18:20:26 GMT 2025`
Record UNII	067U1T4S30
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

BICYCLO(2.2.2)OCTAN-2-OL, 2-(3,4-DICHLOROPHENYL)-3-((1-METHYLETHYL)AMINO)-, CIS-

Preferred Name

English

CILOBAMINE

Official Name

English

CLOBAMINE

Common Name

English

cilobamine [INN]

Common Name

English

CIS-2-(3,4-DICHLOROPHENYL)-3-(ISOPROPYLAMINO)BICYCLO(2.2.2)OCTAN-2-OL

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265

Created by admin on Mon Mar 31 18:20:26 GMT 2025 , Edited by admin on Mon Mar 31 18:20:26 GMT 2025

Code System Code Type Description

WIKIPEDIA

Cilobamine

Created by admin on Mon Mar 31 18:20:26 GMT 2025 , Edited by admin on Mon Mar 31 18:20:26 GMT 2025

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NCI_THESAURUS

C81476

Created by admin on Mon Mar 31 18:20:26 GMT 2025 , Edited by admin on Mon Mar 31 18:20:26 GMT 2025

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PUBCHEM

10381819

Created by admin on Mon Mar 31 18:20:26 GMT 2025 , Edited by admin on Mon Mar 31 18:20:26 GMT 2025

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EPA CompTox

DTXSID001024449

Created by admin on Mon Mar 31 18:20:26 GMT 2025 , Edited by admin on Mon Mar 31 18:20:26 GMT 2025

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FDA UNII

067U1T4S30

Created by admin on Mon Mar 31 18:20:26 GMT 2025 , Edited by admin on Mon Mar 31 18:20:26 GMT 2025

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MESH

C041367

Created by admin on Mon Mar 31 18:20:26 GMT 2025 , Edited by admin on Mon Mar 31 18:20:26 GMT 2025

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INN

4896

Created by admin on Mon Mar 31 18:20:26 GMT 2025 , Edited by admin on Mon Mar 31 18:20:26 GMT 2025

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EVMPD

SUB06269MIG

Created by admin on Mon Mar 31 18:20:26 GMT 2025 , Edited by admin on Mon Mar 31 18:20:26 GMT 2025

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ChEMBL

CHEMBL2110879

Created by admin on Mon Mar 31 18:20:26 GMT 2025 , Edited by admin on Mon Mar 31 18:20:26 GMT 2025

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CAS

69429-84-1

Created by admin on Mon Mar 31 18:20:26 GMT 2025 , Edited by admin on Mon Mar 31 18:20:26 GMT 2025

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SMS_ID

100000081033

Created by admin on Mon Mar 31 18:20:26 GMT 2025 , Edited by admin on Mon Mar 31 18:20:26 GMT 2025

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Related Record Type Details


					SZ83PVQ06I

CILOBAMINE MESYLATE

SALT/SOLVATE -> PARENT

Related Record Type Details


					067U1T4S30

ACTIVE MOIETY