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Details

Stereochemistry RACEMIC
Molecular Formula C17H23Cl2NO
Molecular Weight 328.277
Optical Activity ( + / - )
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CILOBAMINE

SMILES

CC(C)N[C@@H]1C2CCC(CC2)[C@@]1(O)C3=CC=C(Cl)C(Cl)=C3

InChI

InChIKey=MQILJMOEUMZBHK-FIMMUYGNSA-N
InChI=1S/C17H23Cl2NO/c1-10(2)20-16-11-3-5-12(6-4-11)17(16,21)13-7-8-14(18)15(19)9-13/h7-12,16,20-21H,3-6H2,1-2H3/t11?,12?,16-,17-/m1/s1

HIDE SMILES / InChI

Molecular Formula C17H23Cl2NO
Molecular Weight 328.277
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Description
Curator's Comment: https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20030522&CC=WO&NR=03042162A1&KC=A1

Cilobamine is a drug which acts as a norepinephrine-dopamine reuptake inhibitor (NDRI) and has stimulant and antidepressant effects.

Approval Year

PubMed

PubMed

TitleDatePubMed
Dose related induction of the drug metabolizing enzymes of rat liver by cilobamine.
1984 Apr
Patents

Patents

Sample Use Guides

rat: 3, 10, 30, 100, and 300 mg/kg po for 4 days
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:09:17 GMT 2023
Edited
by admin
on Fri Dec 15 16:09:17 GMT 2023
Record UNII
067U1T4S30
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CILOBAMINE
INN  
INN  
Official Name English
CLOBAMINE
Common Name English
cilobamine [INN]
Common Name English
CIS-2-(3,4-DICHLOROPHENYL)-3-(ISOPROPYLAMINO)BICYCLO(2.2.2)OCTAN-2-OL
Common Name English
BICYCLO(2.2.2)OCTAN-2-OL, 2-(3,4-DICHLOROPHENYL)-3-((1-METHYLETHYL)AMINO)-, CIS-
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C265
Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023
Code System Code Type Description
WIKIPEDIA
Cilobamine
Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023
PRIMARY
NCI_THESAURUS
C81476
Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023
PRIMARY
PUBCHEM
10381819
Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023
PRIMARY
EPA CompTox
DTXSID001024449
Created by admin on Fri Dec 15 16:09:17 GMT 2023 , Edited by admin on Fri Dec 15 16:09:17 GMT 2023
PRIMARY
FDA UNII
067U1T4S30
Created by admin on Fri Dec 15 16:09:17 GMT 2023 , Edited by admin on Fri Dec 15 16:09:17 GMT 2023
PRIMARY
MESH
C041367
Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023
PRIMARY
INN
4896
Created by admin on Fri Dec 15 16:09:17 GMT 2023 , Edited by admin on Fri Dec 15 16:09:17 GMT 2023
PRIMARY
EVMPD
SUB06269MIG
Created by admin on Fri Dec 15 16:09:17 GMT 2023 , Edited by admin on Fri Dec 15 16:09:17 GMT 2023
PRIMARY
ChEMBL
CHEMBL2110879
Created by admin on Fri Dec 15 16:09:17 GMT 2023 , Edited by admin on Fri Dec 15 16:09:17 GMT 2023
PRIMARY
CAS
69429-84-1
Created by admin on Fri Dec 15 16:09:17 GMT 2023 , Edited by admin on Fri Dec 15 16:09:17 GMT 2023
PRIMARY
SMS_ID
100000081033
Created by admin on Fri Dec 15 16:09:18 GMT 2023 , Edited by admin on Fri Dec 15 16:09:18 GMT 2023
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
Related Record Type Details
ACTIVE MOIETY