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Details

Stereochemistry ACHIRAL
Molecular Formula C9H10O4
Molecular Weight 182.1733
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FLOPROPIONE

SMILES

CCC(=O)C1=C(O)C=C(O)C=C1O

InChI

InChIKey=PTHLEKANMPKYDB-UHFFFAOYSA-N
InChI=1S/C9H10O4/c1-2-6(11)9-7(12)3-5(10)4-8(9)13/h3-4,10,12-13H,2H2,1H3

HIDE SMILES / InChI

Molecular Formula C9H10O4
Molecular Weight 182.1733
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Flopropione is an antispasmodic agent developed to relieve spasms in patients with hepatobiliary disorders, pancreatitis and urinary calculus. The mode of action is based on the inhibition of catechol-o-methyl-transferase (COMT), resulting in an adrenergic action, and anti-serotonin action. The current marketing status of the drug is unknown and considered to be "discontinued".

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
COSPANON
Primary
COSPANON
Primary
COSPANON
Primary
COSPANON
Primary
COSPANON
Primary
COSPANON
Primary
COSPANON

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
The usual adult dosage for oral use is 1 to 2 capsules (40-80 mg of flopropione) three times daily after meals.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
05V5NVB5Y1
Record Status Validated (UNII)
Record Version