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Details

Stereochemistry ACHIRAL
Molecular Formula C7H11N3O2
Molecular Weight 169.1811
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of IPRONIDAZOLE

SMILES

CC(C)C1=NC=C(N1C)[N+]([O-])=O

InChI

InChIKey=NTAFJUSDNOSFFY-UHFFFAOYSA-N
InChI=1S/C7H11N3O2/c1-5(2)7-8-4-6(9(7)3)10(11)12/h4-5H,1-3H3

HIDE SMILES / InChI

Molecular Formula C7H11N3O2
Molecular Weight 169.1811
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Ipronidazole is an antiprotozoal drug of the nitroimidazole class used in veterinary medicine. Ipronidazole (2-isopropyl-1-methyl-5-nitroimidazole) is used for the treatment of histomoniasis in turkeys and in swine dysentery.

Originator

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
Ipropran

PubMed

Sample Use Guides

In Vivo Use Guide
Ipronidazole is administered through the feed at levels of approximately 0.006253% (prevention) to 0.025% (treatment). Continuous feeding of ipronidazole at a concentration of 100 g/ton in feed has been shown to prevent swine dysentery. Administration of ipronidazole at 200 to 800 mg/gal of drinking water for 7 days was effective in treating swine dysentery.
Route of Administration: Oral
In Vitro Use Guide
2.3 uM/mg protein of Ipronidazole induced a 60% decrease in rabbit heart mitochondrial ADP-stimulated oxygen uptake using glutamate-malate as substrate.
Substance Class Chemical
Record UNII
045BU63E23
Record Status Validated (UNII)
Record Version