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Description

Indium In-111 pentetate disodium is a radioactive diagnostic indicated for use in radionuclide cisternography. Decay of In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and spinal column. Indium In 111 pentetate ( 111In-DTPA) is indicated as an imaging agent in cisternography to study the flow of cerebrospinal fluid (CSF) in the brain, to diagnose abnormalities in CSF circulation, to assess and help localize the site of CSF leakage, and to test the patency of or localize blocks in CSF shunts.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
MPI INDIUM DTPA IN 111
Diagnostic
MPI INDIUM DTPA IN 111
Diagnostic
MPI INDIUM DTPA IN 111

Sample Use Guides

In Vivo Use Guide
The maximum recommended intrathecal dose in the average patient (70 kg) is 18.5 MBq, 500 μCi. The patient dose should be measured by a suitable radioactivity calibration system immediately prior to administration.
Route of Administration: Other
Substance Class Protein
Protein Type MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type IGG1
Sequence Origin MOUSE
Sequence Type COMPLETE
Record UNII
03MZ53X1YS
Record Status Validated (UNII)
Record Version