Indium In-111 pentetate disodium is a radioactive diagnostic indicated for use in radionuclide cisternography. Decay of In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and spinal column. Indium In 111 pentetate ( 111In-DTPA) is indicated as an imaging agent in cisternography to study the flow of cerebrospinal fluid (CSF) in the brain, to diagnose abnormalities in CSF circulation, to assess and help localize the site of CSF leakage, and to test the patency of or localize blocks in CSF shunts.
Approval Year
| Substance Class |
Protein
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| Protein Type | MONOCLONAL ANTIBODY CONJUGATE |
| Protein Sub Type | IGG1 |
| Sequence Origin | MOUSE |
| Sequence Type | COMPLETE |
| Record UNII |
03MZ53X1YS
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| Record Status |
Validated (UNII)
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Code | English | ||
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| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C2124
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WHO-ATC |
V09IB04
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admin on Mon Mar 31 23:03:29 GMT 2025 , Edited by admin on Mon Mar 31 23:03:29 GMT 2025
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| Code System | Code | Type | Description | ||
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C88292
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admin on Mon Mar 31 23:03:29 GMT 2025 , Edited by admin on Mon Mar 31 23:03:29 GMT 2025
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PRIMARY | NCIT | ||
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CHEMBL2108800
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PRIMARY | |||
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03MZ53X1YS
Created by
admin on Mon Mar 31 23:03:29 GMT 2025 , Edited by admin on Mon Mar 31 23:03:29 GMT 2025
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PRIMARY |
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ACTIVE MOIETY | |||
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ACTIVE MOIETY |
Agent Modifications
| Modification Process | Modification Role | Modification Type | Amount | Fragment Name | Fragment ID |
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| OXIDIZES SUGAR | OXIDIZER |
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SODIUM METAPERIODATE | 98W4A29X43 | |
| CHELATING AGENT | CONJUGATION |
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SODIUM METAPERIODATE | 98W4A29X43 |
Structural Modifications
| Modification Type | Location Site | Location Type | Residue Modified | Extent | Fragment Name | Fragment Approval |
|---|---|---|---|---|---|---|
| MOIETY | SUGAR |
Amount:
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INDIUM CATION IN-111 | WJZ06C0H8L |
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| Molecular Formula | CHEMICAL |
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| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
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