ETILAMFETAMINE

Details

Stereochemistry	RACEMIC
Molecular Formula	C11H17N
Molecular Weight	163.2594
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCNC(C)CC1=CC=CC=C1

InChI

InChIKey=YAGBSNMZQKEFCO-UHFFFAOYSA-N

InChI=1S/C11H17N/c1-3-12-10(2)9-11-7-5-4-6-8-11/h4-8,10,12H,3,9H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C11H17N
Molecular Weight	163.2594
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13389142 | https://www.ncbi.nlm.nih.gov/pubmed/12827635 | https://www.whocc.no/atc_ddd_index/?code=A08AA06&showdescription=yes | https://www.ncbi.nlm.nih.gov/pubmed/25548026 | https://www.genome.jp/dbget-bin/www_bget?dr:D07114 | https://www.ncbi.nlm.nih.gov/pubmed/25618172 | http://www.bertin-bioreagent.com/pr6684/n-wbr-ethylamphetamine-hydro-wbr-chloride

Etilamfetamine (Apetinil) is a stimulant drug of amphetamine chemical class. It is an N-substituted amphetamine with an ethyl group on the amphetamine backbone. It was used as an anorectic or appetite suppressant. Etilamfetamine is a psychoactive drug, which can be used as a recreational drug. Etilamfetamine has been abused as a “designer drug” alternative to amphetamine and possibly methamphetamine. It is a dopamine releasing agent.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Dopamine transporter 180 Target ID: CHEMBL238 Sources: https://en.wikipedia.org/wiki/Etilamfetamine \| https://www.ncbi.nlm.nih.gov/pubmed/25548026	Binding Agent 1064

PubMed

Title	Date	PubMed
Evaluation of Roche Abuscreen ONLINE amphetamine immunoassay for screening of new amphetamine analogues.	2001 Sep	11550823
Toxicokinetics of amphetamines: metabolism and toxicokinetic data of designer drugs, amphetamine, methamphetamine, and their N-alkyl derivatives.	2002 Apr	11897973
Evaluating the separation of amphetamines by electrospray ionization ion mobility spectrometry/MS and charge competition within the ESI process.	2002 Jan 15	11811417
Precursor medications as a source of methamphetamine and/or amphetamine positive drug testing results.	2002 May	12024689
Screening for and validated quantification of amphetamines and of amphetamine- and piperazine-derived designer drugs in human blood plasma by gas chromatography/mass spectrometry.	2003 Jun	12827635
Impurity profiling of methamphetamine hydrochloride drugs seized in the Philippines.	2004 Aug 11	15240018
MetaSite: understanding metabolism in human cytochromes from the perspective of the chemist.	2005 Nov 3	16250655
LC-MS/MS screening method for designer amphetamines, tryptamines, and piperazines in serum.	2010 Apr	20069283

Sample Use Guides

In Vivo Use Guide

Rats (Wistar) were injected intraperitoneally with 25 mg ethylamphetamine hydrochloride per kg.

Route of Administration: Intraperitoneal

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:53:02 UTC 2023` Edited by `admin` on `Fri Dec 15 15:53:02 UTC 2023`
Record UNII	022YON1XMX
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ETILAMFETAMINE

Official Name

English

ETHYLAMPHETAMINE

Systematic Name

English

N-ETHYLAMPHETAMINE [MI]

Common Name

English

etilamfetamine [INN]

Common Name

English

Ethylamphetamine [WHO-DD]

Common Name

English

N-ETHYL-.ALPHA.-METHYLPHENETHYLAMINE

Systematic Name

English

Classification Tree Code System Code

DEA NO.

1475