OXINDANAC

Details

Stereochemistry	RACEMIC
Molecular Formula	C17H14O4
Molecular Weight	282.2907
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)C1CCC2=C1C=C(O)C(=C2)C(=O)C3=CC=CC=C3

InChI

InChIKey=XMTKXTUIUKKGIL-UHFFFAOYSA-N

InChI=1S/C17H14O4/c18-15-9-13-11(6-7-12(13)17(20)21)8-14(15)16(19)10-4-2-1-3-5-10/h1-5,8-9,12,18H,6-7H2,(H,20,21)

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2687006 | https://www.ncbi.nlm.nih.gov/pubmed/2603808 | https://adisinsight.springer.com/drugs/800000981

Oxindanac, a non-steroidal anti-inflammatory drug, and is a weak cyclooxygenase inhibitor possessed antipyretic activity. This drug is used as a veterinary inflammatory drug. In addition, oxindanac was studied in phase III clinical trials for the treatment of rheumatic disorders. However, this study was discontinued.

Originator

Approval Year

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

Eight male volunteers receiving frusemide 40 mg b.d. were also given either oxindanac 300 mg b.d. or placebo in two consecutive periods separated by a treatment-free period, according to a randomized cross-over study design.

Route of Administration: Oral

Name

Type

Language

OXINDANAC

Official Name

English

1H-INDENE-1-CARBOXYLIC ACID, 5-BENZOYL-2,3-DIHYDRO-6-HYDROXY-

Systematic Name

English

CGP-6258

Code

English

OXINDANAC [MART.]

Common Name

English

oxindanac [INN]

Common Name

English

5-BENZOYL-6-METHOXY-1-INDANCARBOXYLIC ACID

Systematic Name

English

(±)-5-BENZOYL-6-HYDROXY-1-INDANCARBOXYLIC ACID

Systematic Name

English

OXINDAZAC

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C257