U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C10H11O4.Na
Molecular Weight 218.1817
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM 2-(4-METHOXYPHENOXY)PROPANOATE

SMILES

[Na+].COC1=CC=C(OC(C)C([O-])=O)C=C1

InChI

InChIKey=SKORRGYRKQDXRS-UHFFFAOYSA-M
InChI=1S/C10H12O4.Na/c1-7(10(11)12)14-9-5-3-8(13-2)4-6-9;/h3-7H,1-2H3,(H,11,12);/q;+1/p-1

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Taste enhancements between various amino acids and IMP.
2002 Oct
Different functional roles of T1R subunits in the heteromeric taste receptors.
2004 Sep 28
Valine 738 and lysine 735 in the fifth transmembrane domain of rTas1r3 mediate insensitivity towards lactisole of the rat sweet taste receptor.
2005 Apr 7
Sugar sensing by enterocytes combines polarity, membrane bound detectors and sugar metabolism.
2007 Dec
The binding site for neohesperidin dihydrochalcone at the human sweet taste receptor.
2007 Oct 12
Genetic and molecular basis of individual differences in human umami taste perception.
2009 Aug 21
The sweet taste quality is linked to a cluster of taste fibers in primates: lactisole diminishes preference and responses to sweet in S fibers (sweet best) chorda tympani fibers of M. fascicularis monkey.
2009 Feb 18
Interactions of the sweet-tasting proteins thaumatin and lysozyme with the human sweet-taste receptor.
2009 Jul 8
Phenoxy herbicides and fibrates potently inhibit the human chemosensory receptor subunit T1R3.
2009 Nov 12
Amiloride reduces the sweet taste intensity by inhibiting the human sweet taste receptor.
2010 Jun 25
Expression of Na+/glucose co-transporter 1 (SGLT1) is enhanced by supplementation of the diet of weaning piglets with artificial sweeteners.
2010 Sep
Patents
Name Type Language
SODIUM 2-(4-METHOXYPHENOXY)PROPANOATE
FHFI  
Systematic Name English
ENVISION
Common Name English
SODIUM 2-(4-METHOXYPHENOXY)PROPANOATE [FHFI]
Common Name English
PROPANOIC ACID, 2-(4-METHOXYPHENOXY)-, SODIUM SALT, (±)-
Common Name English
FEMA NO. 3773
Code English
PROPANOIC ACID, 2-(4-METHOXYPHENOXY)-, SODIUM SALT (1:1)
Common Name English
SODIUM 2-(4-METHOXYPHENOXY)PROPIONATE
Systematic Name English
LACTISOLE SODIUM SALT [MI]
Common Name English
Code System Code Type Description
CAS
150436-68-3
Created by admin on Sat Dec 16 00:14:07 GMT 2023 , Edited by admin on Sat Dec 16 00:14:07 GMT 2023
PRIMARY
JECFA MONOGRAPH
962
Created by admin on Sat Dec 16 00:14:07 GMT 2023 , Edited by admin on Sat Dec 16 00:14:07 GMT 2023
PRIMARY
MERCK INDEX
m6658
Created by admin on Sat Dec 16 00:14:07 GMT 2023 , Edited by admin on Sat Dec 16 00:14:07 GMT 2023
PRIMARY Merck Index
SMS_ID
300000031237
Created by admin on Sat Dec 16 00:14:07 GMT 2023 , Edited by admin on Sat Dec 16 00:14:07 GMT 2023
PRIMARY
WIKIPEDIA
Lactisole
Created by admin on Sat Dec 16 00:14:07 GMT 2023 , Edited by admin on Sat Dec 16 00:14:07 GMT 2023
PRIMARY
PUBCHEM
23670520
Created by admin on Sat Dec 16 00:14:07 GMT 2023 , Edited by admin on Sat Dec 16 00:14:07 GMT 2023
PRIMARY
FDA UNII
ZU3D90W5GZ
Created by admin on Sat Dec 16 00:14:07 GMT 2023 , Edited by admin on Sat Dec 16 00:14:07 GMT 2023
PRIMARY
MESH
C495512
Created by admin on Sat Dec 16 00:14:07 GMT 2023 , Edited by admin on Sat Dec 16 00:14:07 GMT 2023
PRIMARY