2-(4-METHOXYPHENOXY)PROPANOIC ACID

Investigational

Details

Stereochemistry	RACEMIC
Molecular Formula	C10H12O4
Molecular Weight	196.1999
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 2-(4-METHOXYPHENOXY)PROPANOIC ACID

Structure Search

SMILES

COC1=CC=C(OC(C)C(O)=O)C=C1

InChI

InChIKey=MIEKOFWWHVOKQX-UHFFFAOYSA-N

InChI=1S/C10H12O4/c1-7(10(11)12)14-9-5-3-8(13-2)4-6-9/h3-7H,1-2H3,(H,11,12)

HIDE SMILES / InChI

Molecular Formula	C10H12O4
Molecular Weight	196.1999
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

PubMed

Title	Date	PubMed
Expression of Na+/glucose co-transporter 1 (SGLT1) is enhanced by supplementation of the diet of weaning piglets with artificial sweeteners.	2010-09	20338074
Amiloride reduces the sweet taste intensity by inhibiting the human sweet taste receptor.	2010-06-25	20493823
Phenoxy herbicides and fibrates potently inhibit the human chemosensory receptor subunit T1R3.	2009-11-12	19817384
Genetic and molecular basis of individual differences in human umami taste perception.	2009-08-21	19696921
Interactions of the sweet-tasting proteins thaumatin and lysozyme with the human sweet-taste receptor.	2009-07-08	19489607
The sweet taste quality is linked to a cluster of taste fibers in primates: lactisole diminishes preference and responses to sweet in S fibers (sweet best) chorda tympani fibers of M. fascicularis monkey.	2009-02-18	19224647
Sugar sensing by enterocytes combines polarity, membrane bound detectors and sugar metabolism.	2007-12	17786952
The binding site for neohesperidin dihydrochalcone at the human sweet taste receptor.	2007-10-12	17935609
Neoculin, a taste-modifying protein, is recognized by human sweet taste receptor.	2006-08-21	16951562
The G protein-coupled receptor subset of the chicken genome.	2006-06-02	16741557
The liaison of sweet and savory.	2006-03	16384922
The heterodimeric sweet taste receptor has multiple potential ligand binding sites.	2006	17168764
Identification of the cyclamate interaction site within the transmembrane domain of the human sweet taste receptor subunit T1R3.	2005-10-07	16076846
Lactisole interacts with the transmembrane domains of human T1R3 to inhibit sweet taste.	2005-04-15	15668251
Valine 738 and lysine 735 in the fifth transmembrane domain of rTas1r3 mediate insensitivity towards lactisole of the rat sweet taste receptor.	2005-04-07	15817126
Bitter taste receptors for saccharin and acesulfame K.	2004-11-10	15537898
Different functional roles of T1R subunits in the heteromeric taste receptors.	2004-09-28	15353592
Taste enhancements between various amino acids and IMP.	2002-10	12379598

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:19:34 GMT 2025` Edited by `admin` on `Mon Mar 31 22:19:34 GMT 2025`
Record UNII	K573UZ6O8U
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

2-(4-METHOXYPHENOXY)PROPANOIC ACID

Systematic Name

English

LACTISOLE

Preferred Name

English

HPMP

Common Name

English

2-(P-METHOXYPHENOXY)PROPIONIC ACID

Systematic Name

English

LACTISOLE [MI]

Common Name

English

NSC-352144

Code

English

PROPANOIC ACID, 2-(4-METHOXYPHENOXY)-

Systematic Name

English

PMP

Common Name

English

LACTISOLE, (±)-

Common Name

English

LACTISOL

Common Name

English

Code System Code Type Description

SMS_ID

100000176793