THYMINE RIBOSIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C10H14N2O6
Molecular Weight	258.228
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=CN([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C(=O)NC1=O

InChI

InChIKey=DWRXFEITVBNRMK-JXOAFFINSA-N

InChI=1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
Differential effects of nucleotide analogs on scanning-dependent initiation and elongation of mammalian mRNA translation in vitro.	2010-06	20423978
Long-term AZT exposure alters the metabolic capacity of cultured human lymphoblastoid cells.	2010-05	20106944
Mutagenesis of the modified bases, m(5)U1939 and psi2504, in Escherichia coli 23S rRNA.	2010-02-05	20067766
A study on the interaction between 5-Methyluridine and human serum albumin using fluorescence quenching method and molecular modeling.	2010-02	19588173
Stereochemical mechanisms of tRNA methyltransferases.	2010-01-21	19944101
Molecularly imprinted polymer of 5-methyluridine for solid-phase extraction of pyrimidine nucleoside cancer markers in urine.	2008-10-01	18789867
Crystallization and preliminary X-ray crystallographic characterization of TrmFO, a folate-dependent tRNA methyltransferase from Thermotoga maritima.	2008-03-01	18323606
Selenium derivatization of nucleic acids for phase and structure determination in nucleic acid X-ray crystallography.	2008-03	19325748
Metabolic signature of breast cancer cell line MCF-7: profiling of modified nucleosides via LC-IT MS coupling.	2007-11-29	18047657
A counterintuitive Mg2+-dependent and modification-assisted functional folding of mitochondrial tRNAs.	2006-09-29	16949614
3D-QSAR studies on antitubercular thymidine monophosphate kinase inhibitors based on different alignment methods.	2006-02-15	16290929
Temperature-dependent biosynthesis of 2-thioribothymidine of Thermus thermophilus tRNA.	2006-01-27	16317006
Synthesis and anti-viral activity of a series of d- and l-2'-deoxy-2'-fluororibonucleosides in the subgenomic HCV replicon system.	2005-03-01	15698782
Kilo-scale synthesis process for 2'-O-(2-methoxyethyl)-pyrimidine derivatives.	2005	16248042
Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase.	2003-09-15	12941330
Three modifications in the D and T arms of tRNA influence translation in Escherichia coli and expression of virulence genes in Shigella flexneri.	2002-10	12218021
Characterization of the 23 S ribosomal RNA m5U1939 methyltransferase from Escherichia coli.	2002-03-15	11779873
Dual function of the tRNA(m(5)U54)methyltransferase in tRNA maturation.	2002-03	12003492
Acquisition of human concentrative nucleoside transporter 2 (hcnt2) activity by gene transfer confers sensitivity to fluoropyrimidine nucleosides in drug-resistant leukemia cells.	2001-11	11641443
Synthesis of novel 3'-C-methylene thymidine and 5-methyluridine/cytidine H-phosphonates and phosphonamidites for new backbone modification of oligonucleotides.	2001-04-20	11304203
Enhanced high density oligonucleotide array-based sequence analysis using modified nucleoside triphosphates.	1998-11-01	9776762
Isolation and identification of apoptosis inducing nucleosides from CD57(+)HLA-DRbright natural suppressor cell line.	1998-10-20	9792789
Purification and characterization of uridine and thymidine phosphorylase from Lactobacillus casei.	1990-09-03	2119230
Characterization of mouse and human monoclonal antibodies cross-reactive with SLE serum antibodies to guanosine.	1984-06	6725946
Specificity of anti-nucleoside antibodies in systemic lupus erythematosus.	1983-06	6603316

Patents

Name

Type

Language

THYMINE RIBOSIDE, (-)-

Preferred Name

English

THYMINE RIBOSIDE

Common Name

English

THYMINE RIBOSIDE [MI]

Common Name

English

RIBOTHYMIDINE

Common Name

English

PYRIMIDINEDIONE, 5-METHYL-1-.BETA.-D-RIBOFURANOSYL-

Systematic Name

English

1-.BETA.-D-RIBOFURANOSYLTHYMINE 2,4(1H,3H)-PYRIMIDINEDIONE, 5-METHYL-1-.BETA.-D-RIBOFURANOSYL-

Systematic Name

English

5-METHYLURIDINE

Systematic Name

English

Code System Code Type Description

EVMPD

SUB197049