SODIUM 2-(4-(2-HYDROXYETHYL)PIPERAZIN-1-YL)ETHANESULFONATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H17N2O4S.Na
Molecular Weight	260.286
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of SODIUM 2-(4-(2-HYDROXYETHYL)PIPERAZIN-1-YL)ETHANESULFONATE

Structure Search

SMILES

[Na+].OCCN1CCN(CCS([O-])(=O)=O)CC1

InChI

InChIKey=RDZTWEVXRGYCFV-UHFFFAOYSA-M

InChI=1S/C8H18N2O4S.Na/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14;/h11H,1-8H2,(H,12,13,14);/q;+1/p-1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/30740472

HYDROXYETHYLPIPERAZINE ETHANE SULFONIC ACID (wider known as HEPES), a zwitterionic buffering agent, is one of the best all-purpose buffers available for use in biological research. HEPES is most effective as a buffer at pH 6.0 to 8.5. It was shown that HEPES could be taken into account as simple and efficient reagent for promoting protein transfection and intracellular targeting and had the potential for myriad clinical applications.

Approval Year

PubMed

Title	Date	PubMed
Utilization of HEPES for Enhancing Protein Transfection into Mammalian Cells.	2019-06-14	30740472
The interference of HEPES buffer during amperometric detection of ATP in clinical applications.	2008-04	18368390
Physiological HEPES buffer proposed as a calibrator for pH measurement in human blood.	1999-05	10418748

Name

Type

Language

SODIUM 2-(4-(2-HYDROXYETHYL)PIPERAZIN-1-YL)ETHANESULFONATE

Systematic Name

English

WAS-14

Preferred Name

English

SODIUM HEPES

Common Name

English

HEPES SODIUM SALT

Common Name

English

1-PIPERAZINEETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-, MONOSODIUM SALT

Systematic Name

English

1-PIPERAZINEETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-, SODIUM SALT (1:1)

Systematic Name

English

Code System Code Type Description

ECHA (EC/EINECS)

278-169-7