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Details

Stereochemistry ACHIRAL
Molecular Formula C8H17N2O4S.Na
Molecular Weight 260.286
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM 2-(4-(2-HYDROXYETHYL)PIPERAZIN-1-YL)ETHANESULFONATE

SMILES

[Na+].OCCN1CCN(CCS([O-])(=O)=O)CC1

InChI

InChIKey=RDZTWEVXRGYCFV-UHFFFAOYSA-M
InChI=1S/C8H18N2O4S.Na/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14;/h11H,1-8H2,(H,12,13,14);/q;+1/p-1

HIDE SMILES / InChI

Molecular Formula C8H17N2O4S
Molecular Weight 237.297
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

HYDROXYETHYLPIPERAZINE ETHANE SULFONIC ACID (wider known as HEPES), a zwitterionic buffering agent, is one of the best all-purpose buffers available for use in biological research. HEPES is most effective as a buffer at pH 6.0 to 8.5. It was shown that HEPES could be taken into account as simple and efficient reagent for promoting protein transfection and intracellular targeting and had the potential for myriad clinical applications.

Approval Year

PubMed

PubMed

TitleDatePubMed
Physiological HEPES buffer proposed as a calibrator for pH measurement in human blood.
1999 May
The interference of HEPES buffer during amperometric detection of ATP in clinical applications.
2008 Apr
Utilization of HEPES for Enhancing Protein Transfection into Mammalian Cells.
2019 Jun 14
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:18:46 UTC 2023
Edited
by admin
on Sat Dec 16 08:18:46 UTC 2023
Record UNII
Z9FTO91O8A
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM 2-(4-(2-HYDROXYETHYL)PIPERAZIN-1-YL)ETHANESULFONATE
Systematic Name English
SODIUM HEPES
Common Name English
HEPES SODIUM SALT
Common Name English
1-PIPERAZINEETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-, MONOSODIUM SALT
Systematic Name English
1-PIPERAZINEETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-, SODIUM SALT (1:1)
Systematic Name English
WAS-14
Code English
Code System Code Type Description
ECHA (EC/EINECS)
278-169-7
Created by admin on Sat Dec 16 08:18:46 UTC 2023 , Edited by admin on Sat Dec 16 08:18:46 UTC 2023
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FDA UNII
Z9FTO91O8A
Created by admin on Sat Dec 16 08:18:46 UTC 2023 , Edited by admin on Sat Dec 16 08:18:46 UTC 2023
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EPA CompTox
DTXSID4044458
Created by admin on Sat Dec 16 08:18:46 UTC 2023 , Edited by admin on Sat Dec 16 08:18:46 UTC 2023
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CAS
75277-39-3
Created by admin on Sat Dec 16 08:18:46 UTC 2023 , Edited by admin on Sat Dec 16 08:18:46 UTC 2023
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PUBCHEM
2724248
Created by admin on Sat Dec 16 08:18:46 UTC 2023 , Edited by admin on Sat Dec 16 08:18:46 UTC 2023
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