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Details

Stereochemistry ABSOLUTE
Molecular Formula C14H22N2O2
Molecular Weight 250.3367
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of RIVASTIGMINE, (R)-

SMILES

CCN(C)C(=O)OC1=CC=CC(=C1)[C@@H](C)N(C)C

InChI

InChIKey=XSVMFMHYUFZWBK-LLVKDONJSA-N
InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m1/s1

HIDE SMILES / InChI
Rivastigmine, (R)- is an impurity of a brain selective acetylcholinesterase inhibitor Rivastigmine. R-Rivastigmine enantiomer is pharmacologically less potent than S-enantiomer, which is used for the treatment of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
A validated chiral liquid chromatographic method for the enantiomeric separation of Rivastigmine hydrogen tartarate, a cholinesterase inhibitor.
2005 Jun 15
Patents

Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Name Type Language
RIVASTIGMINE, (R)-
Common Name English
RIVASTIGMINE TARTRATE R-ISOMER [USP-RS]
Common Name English
(R)-RIVASTIGMINE
Common Name English
RIVASTIGMINE TARTRATE R-ISOMER
USP-RS  
Common Name English
CARBAMIC ACID, N-ETHYL-N-METHYL-, 3-((1R)-1-(DIMETHYLAMINO)ETHYL)PHENYL ESTER
Systematic Name English
RIVASTIGMINE IMPURITY D [EP IMPURITY]
Common Name English
SDZ-212712
Code English
RIVASTIGMINE HYDROGEN TARTRATE IMPURITY D [EP IMPURITY]
Common Name English
Code System Code Type Description
RS_ITEM_NUM
1604847
Created by admin on Sat Dec 16 08:22:17 GMT 2023 , Edited by admin on Sat Dec 16 08:22:17 GMT 2023
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FDA UNII
Z25UDQ15MV
Created by admin on Sat Dec 16 08:22:17 GMT 2023 , Edited by admin on Sat Dec 16 08:22:17 GMT 2023
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CAS
415973-05-6
Created by admin on Sat Dec 16 08:22:17 GMT 2023 , Edited by admin on Sat Dec 16 08:22:17 GMT 2023
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PUBCHEM
12133267
Created by admin on Sat Dec 16 08:22:17 GMT 2023 , Edited by admin on Sat Dec 16 08:22:17 GMT 2023
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EPA CompTox
DTXSID90194422
Created by admin on Sat Dec 16 08:22:17 GMT 2023 , Edited by admin on Sat Dec 16 08:22:17 GMT 2023
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