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Details

Stereochemistry ABSOLUTE
Molecular Formula C14H22N2O2
Molecular Weight 250.3367
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of RIVASTIGMINE, (R)-

SMILES

CCN(C)C(=O)OC1=CC=CC(=C1)[C@@H](C)N(C)C

InChI

InChIKey=XSVMFMHYUFZWBK-LLVKDONJSA-N
InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m1/s1

HIDE SMILES / InChI
Rivastigmine, (R)- is an impurity of a brain selective acetylcholinesterase inhibitor Rivastigmine. R-Rivastigmine enantiomer is pharmacologically less potent than S-enantiomer, which is used for the treatment of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Enantioselective separation of rivastigmine by capillary electrophoresis with cyclodextrines.
2005 Jul 15
Patents

Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Name Type Language
RIVASTIGMINE, (R)-
Common Name English
RIVASTIGMINE TARTRATE R-ISOMER [USP-RS]
Common Name English
(R)-RIVASTIGMINE
Common Name English
RIVASTIGMINE TARTRATE R-ISOMER
USP-RS  
Common Name English
CARBAMIC ACID, N-ETHYL-N-METHYL-, 3-((1R)-1-(DIMETHYLAMINO)ETHYL)PHENYL ESTER
Systematic Name English
RIVASTIGMINE IMPURITY D [EP IMPURITY]
Common Name English
SDZ-212712
Code English
RIVASTIGMINE HYDROGEN TARTRATE IMPURITY D [EP IMPURITY]
Common Name English
Code System Code Type Description
RS_ITEM_NUM
1604847
Created by admin on Sat Dec 16 08:22:17 GMT 2023 , Edited by admin on Sat Dec 16 08:22:17 GMT 2023
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FDA UNII
Z25UDQ15MV
Created by admin on Sat Dec 16 08:22:17 GMT 2023 , Edited by admin on Sat Dec 16 08:22:17 GMT 2023
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CAS
415973-05-6
Created by admin on Sat Dec 16 08:22:17 GMT 2023 , Edited by admin on Sat Dec 16 08:22:17 GMT 2023
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PUBCHEM
12133267
Created by admin on Sat Dec 16 08:22:17 GMT 2023 , Edited by admin on Sat Dec 16 08:22:17 GMT 2023
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EPA CompTox
DTXSID90194422
Created by admin on Sat Dec 16 08:22:17 GMT 2023 , Edited by admin on Sat Dec 16 08:22:17 GMT 2023
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