U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C22H22O9
Molecular Weight 430.4047
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ONONIN

SMILES

COC1=CC=C(C=C1)C2=COC3=CC(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)=CC=C3C2=O

InChI

InChIKey=MGJLSBDCWOSMHL-MIUGBVLSSA-N
InChI=1S/C22H22O9/c1-28-12-4-2-11(3-5-12)15-10-29-16-8-13(6-7-14(16)18(15)24)30-22-21(27)20(26)19(25)17(9-23)31-22/h2-8,10,17,19-23,25-27H,9H2,1H3/t17-,19-,20+,21-,22-/m1/s1

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Determination of 14 chemical constituents in the traditional Chinese medicinal preparation Huangqin-Tang by high performance liquid chromatography.
2001 Jun
A new pterocarpan, (-)-maackiain sulfate, from the roots of Sophora subprostrata.
2003 Dec
Determination and identification of isoflavonoids in Radix astragali by matrix solid-phase dispersion extraction and high-performance liquid chromatography with photodiode array and mass spectrometric detection.
2004 Apr 2
[Studies on the active constituents in vine stem of Spatholobus suberectus].
2005 Jan
Studies of chemical constituents and their antioxidant activities from Astragalus mongholicus Bunge.
2005 Oct
Screening and analysis of the multiple absorbed bioactive components and metabolites of Dangguibuxue decoction by the metabolic fingerprinting technique and liquid chromatography/diode-array detection mass spectrometry.
2007
[Studies on chemical constituents from roots of Caragana microphylla].
2007 Apr
Simultaneous quantification of three isoflavonoid glycosides in rabbit plasma after oral administration of Astragalus mongholicus extract by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.
2007 Oct 29
Simultaneous determination of calycosin-7-O-beta-D-glucoside, ononin, astragaloside IV, astragaloside I and ferulic acid in rat plasma after oral administration of Danggui Buxue Tang extract for their pharmacokinetic studies by liquid chromatography-mass spectrometry.
2008 Apr 1
Protection of PC12 cells against superoxide-induced damage by isoflavonoids from Astragalus mongholicus.
2009 Feb
Astragalus membranaceus flavonoids (AMF) ameliorate chronic fatigue syndrome induced by food intake restriction plus forced swimming.
2009 Feb 25
Simultaneous determination of five flavonoids in licorice using pressurized liquid extraction and capillary electrochromatography coupled with peak suppression diode array detection.
2009 Oct 23
Comparison of the immunoregulatory function of different constituents in radix astragali and radix hedysari.
2010
A comprehensive platform for quality control of botanical drugs (PhytomicsQC): a case study of Huangqin Tang (HQT) and PHY906.
2010 Aug 20
The effective fraction isolated from Radix Astragali alleviates glucose intolerance, insulin resistance and hypertriglyceridemia in db/db diabetic mice through its anti-inflammatory activity.
2010 Aug 24
Calycosin promotes angiogenesis involving estrogen receptor and mitogen-activated protein kinase (MAPK) signaling pathway in zebrafish and HUVEC.
2010 Jul 29
Patents
Name Type Language
ONONIN
MI   USP-RS  
Common Name English
FORMONONETIN 7-O-.BETA.-D-GLUCOSIDE
Common Name English
7-HYDROXY-4'-METHOXYISOFLAVONE-7-O-.BETA.-D-GLUCOSIDE
Common Name English
FORMONONETIN 7-O-GLUCOSIDE
Common Name English
FORMONONETIN 7-O-.BETA.-D-GLUCOPYRANOSIDE
Common Name English
FORMONONETIN 7-GLUCOSIDE
Common Name English
ONONIN [USP-RS]
Common Name English
ONONIN [MI]
Common Name English
ONONIN (CONSTITUENT OF ASTRAGALUS) [DSC]
Common Name English
FORMONONETIN GLUCOSIDE
Common Name English
ONONOSIDE
Common Name English
7-(.BETA.-GLUCOSYLOXY)-3-(4-METHOXYPHENYL)ISOFLAVONE
Common Name English
Code System Code Type Description
PUBCHEM
442813
Created by admin on Sat Dec 16 02:00:47 GMT 2023 , Edited by admin on Sat Dec 16 02:00:47 GMT 2023
PRIMARY
MERCK INDEX
m5541
Created by admin on Sat Dec 16 02:00:47 GMT 2023 , Edited by admin on Sat Dec 16 02:00:47 GMT 2023
PRIMARY Merck Index
EPA CompTox
DTXSID70964089
Created by admin on Sat Dec 16 02:00:47 GMT 2023 , Edited by admin on Sat Dec 16 02:00:47 GMT 2023
PRIMARY
WIKIPEDIA
ONONIN
Created by admin on Sat Dec 16 02:00:47 GMT 2023 , Edited by admin on Sat Dec 16 02:00:47 GMT 2023
PRIMARY
CHEBI
7775
Created by admin on Sat Dec 16 02:00:47 GMT 2023 , Edited by admin on Sat Dec 16 02:00:47 GMT 2023
PRIMARY
FDA UNII
Z0Z637970U
Created by admin on Sat Dec 16 02:00:47 GMT 2023 , Edited by admin on Sat Dec 16 02:00:47 GMT 2023
PRIMARY
CAS
486-62-4
Created by admin on Sat Dec 16 02:00:47 GMT 2023 , Edited by admin on Sat Dec 16 02:00:47 GMT 2023
PRIMARY
RS_ITEM_NUM
1478651
Created by admin on Sat Dec 16 02:00:47 GMT 2023 , Edited by admin on Sat Dec 16 02:00:47 GMT 2023
PRIMARY