Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C22H22O9 |
| Molecular Weight | 430.4047 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 5 / 5 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC=C(C=C1)C2=COC3=C(C=CC(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)=C3)C2=O
InChI
InChIKey=MGJLSBDCWOSMHL-MIUGBVLSSA-N
InChI=1S/C22H22O9/c1-28-12-4-2-11(3-5-12)15-10-29-16-8-13(6-7-14(16)18(15)24)30-22-21(27)20(26)19(25)17(9-23)31-22/h2-8,10,17,19-23,25-27H,9H2,1H3/t17-,19-,20+,21-,22-/m1/s1
| Molecular Formula | C22H22O9 |
| Molecular Weight | 430.4047 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 5 / 5 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Flavonoids from Radix Astragali induce the expression of erythropoietin in cultured cells: a signaling mediated via the accumulation of hypoxia-inducible factor-1α. | 2011-03-09 |
|
| Structural relationship and binding mechanisms of five flavonoids with bovine serum albumin. | 2010-12-09 |
|
| [Chemical constituents from roots of Pueraria lobata]. | 2010-12 |
|
| Preventive effects of Flos Perariae (Gehua) water extract and its active ingredient puerarin in rodent alcoholism models. | 2010-10-26 |
|
| [Simultaneous assay of four isoflavonoids in Astragali Radix by QAMS]. | 2010-10 |
|
| [Simultaneous determination of nine isoflavonoids in Huangqi Gegen decoction by high performance liquid chromatography]. | 2010-10 |
|
| The effective fraction isolated from Radix Astragali alleviates glucose intolerance, insulin resistance and hypertriglyceridemia in db/db diabetic mice through its anti-inflammatory activity. | 2010-08-24 |
|
| A comprehensive platform for quality control of botanical drugs (PhytomicsQC): a case study of Huangqin Tang (HQT) and PHY906. | 2010-08-20 |
|
| Calycosin promotes angiogenesis involving estrogen receptor and mitogen-activated protein kinase (MAPK) signaling pathway in zebrafish and HUVEC. | 2010-07-29 |
|
| Chemical analysis of the principal flavonoids of Radix Hedysari by HPLC. | 2010-04 |
|
| Comparison of the immunoregulatory function of different constituents in radix astragali and radix hedysari. | 2010 |
|
| [Isoflavones from vines of Pueraria lobata]. | 2009-12 |
|
| Simultaneous determination of five flavonoids in licorice using pressurized liquid extraction and capillary electrochromatography coupled with peak suppression diode array detection. | 2009-10-23 |
|
| Stimulating effects of Bacillus subtilis natto-fermented Radix astragali on hyaluronic acid production in human skin cells. | 2009-09-25 |
|
| Isolation and purification of flavonoid glucosides from Radix Astragali by high-speed counter-current chromatography. | 2009-03-15 |
|
| Astragalus membranaceus flavonoids (AMF) ameliorate chronic fatigue syndrome induced by food intake restriction plus forced swimming. | 2009-02-25 |
|
| Protection of PC12 cells against superoxide-induced damage by isoflavonoids from Astragalus mongholicus. | 2009-02 |
|
| [Isoflavones from Millettia nitida var. hirsutissima]. | 2009-02 |
|
| [Isoflavone glycosides from the bark of Maackia amurensis]. | 2009-01 |
|
| Composite Medicago truncatula plants harbouring Agrobacterium rhizogenes-transformed roots reveal normal mycorrhization by Glomus intraradices. | 2009 |
|
| Isoflavonoid composition of a callus culture of the relict tree Maackia amurensis Rupr. et Maxim. | 2008-08-27 |
|
| Chemical markers for the quality control of herbal medicines: an overview. | 2008-06-28 |
|
| Ultrahigh-pressure liquid chromatography of isoflavones and phenolic acids on different stationary phases. | 2008-06-27 |
|
| Chemical comparison and classification of Radix Astragali by determination of isoflavonoids and astragalosides. | 2008-06-09 |
|
| Simultaneous determination of calycosin-7-O-beta-D-glucoside, ononin, astragaloside IV, astragaloside I and ferulic acid in rat plasma after oral administration of Danggui Buxue Tang extract for their pharmacokinetic studies by liquid chromatography-mass spectrometry. | 2008-04-01 |
|
| Determination of nine active components in Radix Hedysari and Radix Astragali using capillary HPLC with diode array detection and MS detection. | 2008-02 |
|
| Metabolite profiling of mycorrhizal roots of Medicago truncatula. | 2008-01 |
|
| Rapid-resolution HPLC with spectrometric detection for the determination and identification of isoflavones in soy preparations and plant extracts. | 2007-12 |
|
| Combined effects of fangchinoline from Stephania tetrandra Radix and formononetin and calycosin from Astragalus membranaceus Radix on hyperglycemia and hypoinsulinemia in streptozotocin-diabetic mice. | 2007-11 |
|
| Simultaneous quantification of three isoflavonoid glycosides in rabbit plasma after oral administration of Astragalus mongholicus extract by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry. | 2007-10-29 |
|
| Analysis of interaction property of bioactive components in Danggui Buxue Decoction with protein by microdialysis coupled with HPLC-DAD-MS. | 2007-06-01 |
|
| [Studies on chemical constituents from roots of Caragana microphylla]. | 2007-04 |
|
| Blockade of cytokine-induced endothelial cell adhesion molecule expression by licorice isoliquiritigenin through NF-kappaB signal disruption. | 2007-02 |
|
| Screening and analysis of the multiple absorbed bioactive components and metabolites of Dangguibuxue decoction by the metabolic fingerprinting technique and liquid chromatography/diode-array detection mass spectrometry. | 2007 |
|
| Quality evaluation of Radix Astragali through a simultaneous determination of six major active isoflavonoids and four main saponins by high-performance liquid chromatography coupled with diode array and evaporative light scattering detectors. | 2006-11-17 |
|
| Quantification and stability studies on the flavonoids of Radix hedysari. | 2006-09-06 |
|
| Screening and identification of permeable components in a combined prescription of Danggui Buxue decoction using a liposome equilibrium dialysis system followed by HPLC and LC-MS. | 2006-09 |
|
| [A new natural product from the roots of Hedysarum multijugum]. | 2005-10-18 |
|
| Studies of chemical constituents and their antioxidant activities from Astragalus mongholicus Bunge. | 2005-10 |
|
| Determination of isoflavones in soy bits by fast column high-performance liquid chromatography coupled with UV-visible diode-array detection. | 2005-08-19 |
|
| Supercritical fluid extraction of isoflavones from biological samples with ultra-fast high-performance liquid chromatography/mass spectrometry. | 2005-08 |
|
| Evaluation of isoflavone aglycon and glycoside distribution in soy plants and soybeans by fast column high-performance liquid chromatography coupled with a diode-array detector. | 2005-07-27 |
|
| Isoflavonoids are present in Arabidopsis thaliana despite the absence of any homologue to known isoflavonoid synthases. | 2005-05-30 |
|
| Isoflavonoids from Astragalus mongholicus protect PC12 cells from toxicity induced by L-glutamate. | 2005-04-08 |
|
| Capillary liquid chromatography-microcoil 1H nuclear magnetic resonance spectroscopy and liquid chromatography-ion trap mass spectrometry for on-line structure elucidation of isoflavones in Radix astragali. | 2005-03-04 |
|
| [Studies on the active constituents in vine stem of Spatholobus suberectus]. | 2005-01 |
|
| Isoflavonoids in the Rutaceae family: 1. Fortunella obovata, Murraya paniculata and four Citrus species. | 2004-10-29 |
|
| Determination and identification of isoflavonoids in Radix astragali by matrix solid-phase dispersion extraction and high-performance liquid chromatography with photodiode array and mass spectrometric detection. | 2004-04-02 |
|
| A new pterocarpan, (-)-maackiain sulfate, from the roots of Sophora subprostrata. | 2003-12 |
|
| [Studies on chemical constituents of Hedysarum polybotrys]. | 2003-08 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:06:25 GMT 2025
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| Record UNII |
Z0Z637970U
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| Record Status |
Validated (UNII)
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| Record Version |
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m5541
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DTXSID70964089
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