ORTHOCRESOL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H8O
Molecular Weight	108.1378
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

CC1=CC=CC=C1O

InChI

InChIKey=QWVGKYWNOKOFNN-UHFFFAOYSA-N

InChI=1S/C7H8O/c1-6-4-2-3-5-7(6)8/h2-5,8H,1H3

HIDE SMILES / InChI

Description

o-Cresol (o-methylphenol) is organic compound, derived from coal tar and crude or obtained synthetically by alkylation of phenol with methanol. Cresol is used in manufacturing of phenolic and epoxy resins, herbicides (dinitrocresols, MCPA, MCPP), rubber, dyes, deodorizing compounds, pharmaceuticals. o-Cresol is also used as antiseptic and disinfectant.

CNS Activity

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2,596

PubMed

Show entries

Title	Date	PubMed
Isolation and characterization of a thermotolerant bacterium Ralstonia sp. strain PHS1 that degrades benzene, toluene, ethylbenzene, and o-xylene.	2001 Jul	11499943
[Using genetic algorithm for quantitative analysis of overlapped spectra in FTIR].	2001 Oct	12945308
[Evaluation of urinary ortho-cresol as biological monitoring indicator of occupational exposure to toluene].	2002 Jun	14694640
An autopsy case of poisoning by massive absorption of cresol a short time before death.	2002 Mar 28	11955837
Metabolism of benzyl alcohol via catechol ortho-pathway in methylnaphthalene-degrading Pseudomonas putida CSV86.	2003 Oct	12687299

Showing 1 to 5 of 9 entries

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Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Escherichia coli HUT-8032* and Staphylococcus aureus AM-1058* were used as the test organisms to study effect of o-cresol. Minimal inhibition concentration of o-cresol required to inhibit bacterial growth for 48 hours at 30°C was 20 mM/kg-water.

Show entries

Name

Type

Language

ORTHOCRESOL

Systematic Name

English

O-CRESOL

Preferred Name

English

CRESOL, O-

Common Name

English

FEMA NO. 3480

Code

English

O-CRESOL [MI]

Common Name

English

Showing 1 to 5 of 20 entries

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Show entries

Classification Tree

Code System

Code

FUNCTIONAL CLASSIFICATION

JECFA EVALUATION

O-CRESOL

Organic Chemical

NCI_THESAURUS

C45494

Showing 1 to 2 of 2 entries

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Show entries

Code System

Code

Type

Description

MERCK INDEX

m3834

PRIMARY

Merck Index

CAS

95-48-7

PRIMARY

ChEMBL

CHEMBL46931

PRIMARY

EPA CompTox

DTXSID8021808

PRIMARY

HSDB

1813

PRIMARY

Showing 1 to 5 of 17 entries

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SUBSTANCE RECORD


					YW84DH5I7U

ORTHOCRESOL