Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C7H8O |
| Molecular Weight | 108.1378 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=CC=CC=C1O
InChI
InChIKey=QWVGKYWNOKOFNN-UHFFFAOYSA-N
InChI=1S/C7H8O/c1-6-4-2-3-5-7(6)8/h2-5,8H,1H3
| Molecular Formula | C7H8O |
| Molecular Weight | 108.1378 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
DescriptionSources: http://www.inchem.org/documents/sids/sids/95487.pdfCurator's Comment: description was created based on several sources, including
http://www.tandfonline.com/doi/abs/10.1080/00021369.1962.10858009
Sources: http://www.inchem.org/documents/sids/sids/95487.pdf
Curator's Comment: description was created based on several sources, including
http://www.tandfonline.com/doi/abs/10.1080/00021369.1962.10858009
o-Cresol (o-methylphenol) is organic compound, derived from coal tar and crude or obtained synthetically by alkylation of phenol with methanol. Cresol is used in manufacturing of phenolic and epoxy resins, herbicides (dinitrocresols, MCPA, MCPP), rubber, dyes, deodorizing compounds, pharmaceuticals. o-Cresol is also used as antiseptic and disinfectant.
CNS Activity
Sources: https://www.ncbi.nlm.nih.gov/pubmed/493719
Curator's Comment: Known to be CNS penetrant in rats. Human data not available.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Improving the bioremediation of phenolic wastewaters by Trametes versicolor. | 2007-02 |
|
| Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. | 2006-11 |
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| Analysis of bioavailable phenols from natural samples by recombinant luminescent bacterial sensors. | 2006-09 |
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| Biodegradation of a phenolic mixture in a solid-liquid two-phase partitioning bioreactor. | 2006-09 |
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| Recycling of agricultural solid waste, coir pith: removal of anions, heavy metals, organics and dyes from water by adsorption onto ZnCl2 activated coir pith carbon. | 2006-07-31 |
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| Removal of soluble organics from water by a hybrid process of clay adsorption and membrane filtration. | 2006-07-31 |
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| Franck-Condon simulations of clusters: phenol-nitrogen. | 2006-04-13 |
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| Occupational exposure to toluene and its possible causative role in renal damage development in shoe workers. | 2006-03 |
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| Synthetic smooth muscle cell phenotype is associated with increased nicotinamide adenine dinucleotide phosphate oxidase activity: effect on collagen secretion. | 2006-02 |
|
| Matrix isolation investigation of the photochemical reaction of methyl-substituted benzenes with CrCl2O2. | 2006-01-26 |
|
| Alanine 101 and alanine 110 of the alpha subunit of Pseudomonas stutzeri OX1 toluene-o-xylene monooxygenase influence the regiospecific oxidation of aromatics. | 2005-12-05 |
|
| Isolation and characterization of solvent-tolerant Pseudomonas putida strain T-57, and its application to biotransformation of toluene to cresol in a two-phase (organic-aqueous) system. | 2005-12 |
|
| The haloperoxidase of the agaric fungus Agrocybe aegerita hydroxylates toluene and naphthalene. | 2005-11-07 |
|
| Guest-induced supramolecular isomerism in inclusion complexes of T-shaped host 4,4-bis(4'-hydroxyphenyl)cyclohexanone. | 2005-11-04 |
|
| Multivariate statistics of the pyrolysis products of high molecular components in pulping wastewaters to explain their toxicity. | 2005-11 |
|
| Highly efficient nitration of phenolic compounds in solid phase or solution using Bi(NO3)3.5H2O as nitrating reagent. | 2005-10-28 |
|
| Effect of temperature and additional carbon sources on phenol degradation by an indigenous soil Pseudomonad. | 2005-10 |
|
| Freeze-dried recombinant bacteria for on-site detection of phenolic compounds by color change. | 2005-09-22 |
|
| Crystal structures and spectroscopic properties of polycyano-polycadmate host clathrates including a CT complex guest of methylviologen dication and aromatic donor. | 2005-09-21 |
|
| Structural features of phenol derivatives determining potency for activation of chloride currents via alpha(1) homomeric and alpha(1)beta heteromeric glycine receptors. | 2005-08 |
|
| Communication and re-use of chemical information in bioscience. | 2005-07-18 |
|
| The Missoula Valley semivolatile and volatile organic compound study: seasonal average concentrations. | 2005-07 |
|
| Adsorption of single-ring organic compounds to wood charcoals prepared under different thermochemical conditions. | 2005-06-01 |
|
| [Photocatalytic degradation of DBPs in aqueous solutions]. | 2005-05 |
|
| Simultaneous determination of phenolic compounds by means of an automated voltammetric "electronic tongue". | 2005-05 |
|
| Biodegradation of phenol and phenol-related compounds by psychrophilic and cold-tolerant alpine yeasts. | 2005-05 |
|
| Effects of air pollutants on childhood asthma. | 2005-04-30 |
|
| Inhibition of cyclooxygenase activity, platelet aggregation and thromboxane B2 production by two environmental toxicants: m- and o-cresol. | 2005-03-01 |
|
| Effect of testosterone and steroids homologues on indolamines and lipid peroxidation in rat brain. | 2005-03 |
|
| Chemotaxis of Pseudomonas stutzeri OX1 and Burkholderia cepacia G4 toward chlorinated ethenes. | 2005-03 |
|
| Effect of toluene and cresols on Na+,K+-ATPase, and serotonin in rat brain. | 2005-02 |
|
| Induction of apoptosis in human promyelocytic leukemia cell line HL-60 by C-benzylated dihydrochalcones, uvaretin, isouvaretin and diuvaretin. | 2005-01 |
|
| Phenolic refinery wastewater biodegradation by an expanded granular sludge bed reactor. | 2005 |
|
| Fabrication and optimization of methylphenoxy substituted polyphosphazene nanofibers for biomedical applications. | 2004-11-09 |
|
| Intramolecularly hydrogen-bonded versus copper(II) coordinated mono- and bis-phenoxyl radicals. | 2004-09-07 |
|
| Exponential modeling, washout curve reconstruction, and estimation of half-life of toluene and its metabolites. | 2004-07-23 |
|
| Synthesis of photo-luminescent Zn(II) Schiff base complexes and its derivative containing Pd(II) moiety. | 2004-06-07 |
|
| Structural models for the reduced form of vanadate-dependent peroxidases: vanadyl complexes with bidentate chiral Schiff base ligands. | 2004-05 |
|
| Adsorption of phenolics on activated carbon--impact of pore size and molecular oxygen. | 2004-05 |
|
| [Extraction of 2-methyl-hydroxybenzene and 3-methyl-hydroxybenzene from water solutions]. | 2004-04-28 |
|
| Degradation of phenol and cresols at low temperatures using a suspended-carrier biofilm process. | 2004-04 |
|
| Platelet activating factor receptor binding plays a critical role in jet fuel-induced immune suppression. | 2004-03-15 |
|
| Benzylmercapturic acid is superior to hippuric acid and o-cresol as a urinary marker of occupational exposure to toluene. | 2004-03-01 |
|
| Quantitative analysis of cresol and its metabolites in biological materials and distribution in rats after oral administration. | 2004-03 |
|
| Assessment of DNA damage in glue sniffers by use of the alkaline comet assay. | 2004-02-14 |
|
| Antifungal cobalt(II), copper(II), nickel(II) and zinc(II) complexes of furanyl-,thiophenyl-, pyrrolyl-, salicylyl- and pyridyl-derived cephalexins. | 2004-02 |
|
| Binding of transition metal ions [cobalt, copper, nickel and zinc] with furanyl-, thiophenyl-, pyrrolyl-, salicylyl- and pyridyl-derived cephalexins as potent antibacterial agents. | 2004-02 |
|
| Determination of phenol and o-cresol by GC/MS in a fatal poisoning case. | 2004-01-28 |
|
| Phenol and lactone receptors in the distal sensilla of the Haller's organ in Ixodes ricinus ticks and their possible role in host perception. | 2004 |
|
| Combined photo-assisted and biological treatment of industrial oily wastewater. | 2004 |
Patents
| Substance Class |
Chemical
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| Record UNII |
YW84DH5I7U
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Validated (UNII)
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JECFA EVALUATION |
O-CRESOL
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NCI_THESAURUS |
C45494
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m3834
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95-48-7
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C80609
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O-CRESOL
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36809
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