Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H9NO2 |
| Molecular Weight | 127.1412 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)C1=CCNCC1
InChI
InChIKey=KRVDMABBKYMBHG-UHFFFAOYSA-N
InChI=1S/C6H9NO2/c8-6(9)5-1-3-7-4-2-5/h1,7H,2-4H2,(H,8,9)
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| GABA(B) receptor autoradiography in hippocampal sclerosis associated with human temporal lobe epilepsy. | 2001 Jan |
|
| GABAA receptor subunit interactions important for benzodiazepine and zinc modulation: a patch-clamp and single cell RT-PCR study. | 2001 May |
|
| Specific GABA(A) agonists and partial agonists. | 2002 |
|
| GABA(A) receptor ligands and their therapeutic potentials. | 2002 Aug |
|
| Pharmacology of GABA(A) receptors exhibiting different levels of spontaneous activity. | 2003 Aug 22 |
|
| Nociception attenuates parasympathetic but not sympathetic baroreflex via NK1 receptors in the rat nucleus tractus solitarii. | 2003 Sep 1 |
|
| In vitro effect of gamma-aminobutyric acid on bovine spermatozoa capacitation. | 2004 Apr |
|
| Developmental changes in GABAergic actions and seizure susceptibility in the rat hippocampus. | 2004 Feb |
|
| Insights into GABA receptor signalling in TM3 Leydig cells. | 2005 |
|
| Mechanisms of hyperpolarizing effect of GABA on resting potential of the Lumbricus terrestris muscular wall somatic cells. | 2005 Feb |
|
| Dopamine depletion alters responses to glutamate and GABA in the rat subthalamic nucleus. | 2005 Feb 8 |
|
| Potent 4-aryl- or 4-arylalkyl-substituted 3-isoxazolol GABA(A) antagonists: synthesis, pharmacology, and molecular modeling. | 2005 Jan 27 |
|
| The Kölliker-Fuse nucleus gates the postinspiratory phase of the respiratory cycle to control inspiratory off-switch and upper airway resistance in rat. | 2006 Aug |
|
| Modulation of GABAergic synaptic transmission by terminal nicotinic acetylcholine receptors in the central autonomic nucleus of the neonatal rat spinal cord. | 2006 Jul |
|
| Subthalamic stimulation evokes complex EPSCs in the rat substantia nigra pars reticulata in vitro. | 2006 Jun 15 |
|
| GABA-induced calcium signaling in cultured enteric neurons is reinforced by activation of cholinergic pathways. | 2006 May 12 |
|
| A spinal vasopressinergic mechanism mediates hyperosmolality-induced sympathoexcitation. | 2006 Oct 15 |
|
| Timing of the developmental switch in GABA(A) mediated signaling from excitation to inhibition in CA3 rat hippocampus using gramicidin perforated patch and extracellular recordings. | 2007 |
|
| Shunting and hyperpolarizing GABAergic inhibition in the high-potassium model of ictogenesis in the developing rat hippocampus. | 2007 |
|
| Endogenous GABA and glutamate finely tune the bursting of olfactory bulb external tufted cells. | 2007 Aug |
|
| Differences in kinetics of structurally related competitive GABA(A) receptor antagonists. | 2007 Mar |
|
| The neurotransmitter GABA is a potent inhibitor of the stromal cell-derived factor-1alpha induced migration of adult CD133+ hematopoietic stem and progenitor cells. | 2007 Oct |
|
| Expression of gamma-aminobutyric acid receptor (subtype A) in prostate cancer. | 2008 |
|
| Population patch-clamp electrophysiology analysis of recombinant GABAA alpha1beta3gamma2 channels expressed in HEK-293 cells. | 2009 Aug |
|
| Control of GABA Release at Mossy Fiber-CA3 Connections in the Developing Hippocampus. | 2010 |
|
| The K+-Cl cotransporter KCC2 promotes GABAergic excitation in the mature rat hippocampus. | 2010 May 1 |
|
| Loss of leptin receptors on hypothalamic POMC neurons alters synaptic inhibition. | 2010 Nov |
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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64603-90-3
Created by
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YTF580771Y
Created by
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C015300
Created by
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3765
Created by
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DTXSID30214855
Created by
admin on Fri Dec 15 19:49:49 GMT 2023 , Edited by admin on Fri Dec 15 19:49:49 GMT 2023
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Isoguvacine
Created by
admin on Fri Dec 15 19:49:49 GMT 2023 , Edited by admin on Fri Dec 15 19:49:49 GMT 2023
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SUBSTANCE RECORD
