U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C15H23N.ClH
Molecular Weight 253.811
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PROLINTANE HYDROCHLORIDE

SMILES

Cl.CCCC(CC1=CC=CC=C1)N2CCCC2

InChI

InChIKey=FKOFBBOQSMUYHD-UHFFFAOYSA-N
InChI=1S/C15H23N.ClH/c1-2-8-15(16-11-6-7-12-16)13-14-9-4-3-5-10-14;/h3-5,9-10,15H,2,6-8,11-13H2,1H3;1H

HIDE SMILES / InChI
Prolintane is an amphetamine-related CNS stimulant and norepinephrine-dopamine reuptake inhibitor that has been used for the treatment of narcolepsy and attention deficit hyperactivity disorder in Africa, Australia, and Europe. Under the trade-name "Katovit", prolintane was commercialized by the Spanish pharmaceutical company, FHER. Katovit was sold until 2001 and was most often used by students and workers as a stimulant to provide energy, promote alertness and concentration. The use of prolintane as a doping agent in athletics has been noted worldwide. Prolintane, like many amphetamine derivatives, increases the concentration of dopamine in the synaptic cleft. Adverse effects of the drug include insomnia, nervousness, irritability, and dizziness. Overdoses of prolintane may cause hallucinations, psychosis, and death. Individuals who abuse prolintane risk becoming dependent as tolerance may develop.

Approval Year

PubMed

PubMed

TitleDatePubMed
[New drugs at "rave parties": ketamine and prolintane].
2002
Application of comprehensive two-dimensional gas chromatography to drugs analysis in doping control.
2003 Jun 6
[Sleeplessness. Helping with paradoxical medication].
2005 Dec 8
Domestic abuse of the European rave drug prolintane.
2007 Sep
Simultaneous analysis of fourteen tertiary amine stimulants in human urine for doping control purposes by liquid chromatography-tandem mass spectrometry and gas chromatography-mass spectrometry.
2010 Jan 4
Name Type Language
PROLINTANE HYDROCHLORIDE
MART.   MI   USAN   WHO-DD  
USAN  
Official Name English
PROLINTANE HYDROCHLORIDE [USAN]
Common Name English
PYRROLIDINE, 1-(1-(PHENYLMETHYL)BUTYL)-, HYDROCHLORIDE
Systematic Name English
VILESCON
Brand Name English
KATOVIT
Brand Name English
Prolintane hydrochloride [WHO-DD]
Common Name English
KATOVIT N
Brand Name English
PROMOTIL
Brand Name English
PROLINTANE HYDROCHLORIDE [MART.]
Common Name English
PROLINTANE HYDROCHLORIDE [MI]
Common Name English
1-(α-Propylphenethyl)pyrrolidine hydrochloride
Systematic Name English
SP-732
Code English
CATOVITAN
Brand Name English
VILLESCON
Brand Name English
NSC-169914
Code English
PYRROLIDINE, 1-(1-BENZYLBUTYL)-, HYDROCHLORIDE
Systematic Name English
Code System Code Type Description
RXCUI
235831
Created by admin on Fri Dec 15 15:05:39 GMT 2023 , Edited by admin on Fri Dec 15 15:05:39 GMT 2023
PRIMARY RxNorm
NSC
169914
Created by admin on Fri Dec 15 15:05:39 GMT 2023 , Edited by admin on Fri Dec 15 15:05:39 GMT 2023
PRIMARY
EVMPD
SUB04064MIG
Created by admin on Fri Dec 15 15:05:39 GMT 2023 , Edited by admin on Fri Dec 15 15:05:39 GMT 2023
PRIMARY
CAS
1211-28-5
Created by admin on Fri Dec 15 15:05:39 GMT 2023 , Edited by admin on Fri Dec 15 15:05:39 GMT 2023
PRIMARY
PUBCHEM
14591
Created by admin on Fri Dec 15 15:05:39 GMT 2023 , Edited by admin on Fri Dec 15 15:05:39 GMT 2023
PRIMARY
MESH
C005598
Created by admin on Fri Dec 15 15:05:39 GMT 2023 , Edited by admin on Fri Dec 15 15:05:39 GMT 2023
PRIMARY
FDA UNII
YEG124534B
Created by admin on Fri Dec 15 15:05:39 GMT 2023 , Edited by admin on Fri Dec 15 15:05:39 GMT 2023
PRIMARY
SMS_ID
100000085104
Created by admin on Fri Dec 15 15:05:39 GMT 2023 , Edited by admin on Fri Dec 15 15:05:39 GMT 2023
PRIMARY
ChEMBL
CHEMBL2111047
Created by admin on Fri Dec 15 15:05:39 GMT 2023 , Edited by admin on Fri Dec 15 15:05:39 GMT 2023
PRIMARY
NCI_THESAURUS
C170357
Created by admin on Fri Dec 15 15:05:39 GMT 2023 , Edited by admin on Fri Dec 15 15:05:39 GMT 2023
PRIMARY
ECHA (EC/EINECS)
214-917-0
Created by admin on Fri Dec 15 15:05:39 GMT 2023 , Edited by admin on Fri Dec 15 15:05:39 GMT 2023
PRIMARY
MERCK INDEX
m9166
Created by admin on Fri Dec 15 15:05:39 GMT 2023 , Edited by admin on Fri Dec 15 15:05:39 GMT 2023
PRIMARY Merck Index
CAS
141996-82-9
Created by admin on Fri Dec 15 15:05:39 GMT 2023 , Edited by admin on Fri Dec 15 15:05:39 GMT 2023
SUPERSEDED