MATAIRESINOL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H22O6
Molecular Weight	358.3851
Optical Activity	( - )
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MATAIRESINOL

Structure Search

SMILES

[H][C@]2(CC1=CC=C(O)C(OC)=C1)COC(=O)[C@]2([H])CC3=CC(OC)=C(O)C=C3

InChI

InChIKey=MATGKVZWFZHCLI-LSDHHAIUSA-N

InChI=1S/C20H22O6/c1-24-18-9-12(3-5-16(18)21)7-14-11-26-20(23)15(14)8-13-4-6-17(22)19(10-13)25-2/h3-6,9-10,14-15,21-22H,7-8,11H2,1-2H3/t14-,15+/m0/s1

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
inflammatory response 47 Target ID: GO:0006954 Sources: https://www.ncbi.nlm.nih.gov/pubmed/28512713	Inhibitor 8297
reactive oxygen species metabolic process 68 Target ID: GO:0072593 Sources: https://www.ncbi.nlm.nih.gov/pubmed/22483751	Modulator 828
Casein kinase I, rat 1 Target ID: Casein kinase I, rat Sources: https://www.ncbi.nlm.nih.gov/pubmed/12612451	Inhibitor 8297		10.0 µM [IC50]
nitric oxide biosynthetic process 17 Target ID: GO:0006809 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27774796	Inhibitor 8297		11.5 µM [IC50]
IL-6/STAT3 pathway 1 Target ID: IL-6/STAT3 pathway Sources: https://www.ncbi.nlm.nih.gov/pubmed/25100250	Inhibitor 8297		2.92 µM [IC50]

PubMed

PubMed

Title	Date	PubMed

Name

Type

Language

MATAIRESINOL

Official Name

English

(-)-MATAIRESINOL

Common Name

English

FEMA NO. 4762

Code

English

2(3H)-FURANONE, DIHYDRO-3,4-BIS((4-HYDROXY-3-METHOXYPHENYL)METHYL)-, (3R,4R)-

Systematic Name

English

(8R,8'R)-(-)-MATAIRESINOL

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C63638

Created by admin on Sat Dec 16 09:52:50 GMT 2023 , Edited by admin on Sat Dec 16 09:52:50 GMT 2023

Code System Code Type Description

DRUG BANK

DB04200

Created by admin on Sat Dec 16 09:52:50 GMT 2023 , Edited by admin on Sat Dec 16 09:52:50 GMT 2023

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JECFA MONOGRAPH

2183

Created by admin on Sat Dec 16 09:52:50 GMT 2023 , Edited by admin on Sat Dec 16 09:52:50 GMT 2023

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CHEBI

6698

Created by admin on Sat Dec 16 09:52:50 GMT 2023 , Edited by admin on Sat Dec 16 09:52:50 GMT 2023

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WIKIPEDIA

Matairesinol

Created by admin on Sat Dec 16 09:52:50 GMT 2023 , Edited by admin on Sat Dec 16 09:52:50 GMT 2023

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EPA CompTox

DTXSID40920490

Created by admin on Sat Dec 16 09:52:50 GMT 2023 , Edited by admin on Sat Dec 16 09:52:50 GMT 2023

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FDA UNII

XLW63P8WUA

Created by admin on Sat Dec 16 09:52:50 GMT 2023 , Edited by admin on Sat Dec 16 09:52:50 GMT 2023

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NCI_THESAURUS

C68496

Created by admin on Sat Dec 16 09:52:50 GMT 2023 , Edited by admin on Sat Dec 16 09:52:50 GMT 2023

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PUBCHEM

119205

Created by admin on Sat Dec 16 09:52:50 GMT 2023 , Edited by admin on Sat Dec 16 09:52:50 GMT 2023

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CAS

580-72-3

Created by admin on Sat Dec 16 09:52:50 GMT 2023 , Edited by admin on Sat Dec 16 09:52:50 GMT 2023

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ACTIVE MOIETY


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