U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C6H6N4O4.ClH
Molecular Weight 234.597
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2,4-DINITROPHENYLHYDRAZINE HYDROCHLORIDE

SMILES

Cl.NNC1=C(C=C(C=C1)[N+]([O-])=O)[N+]([O-])=O

InChI

InChIKey=PUYFAZQODQZOFK-UHFFFAOYSA-N
InChI=1S/C6H6N4O4.ClH/c7-8-5-2-1-4(9(11)12)3-6(5)10(13)14;/h1-3,8H,7H2;1H

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Azole. 45(1). Uber 2,4-Dinitrophenylhydrazone von Morpholinonitroimidazolderivaten.
2001 Apr
Determination of aldehydes and ketones in air samples using cryotrapping sampling.
2001 Aug
Volatile organic compound measurements in the California/Mexico border region during SCOS97.
2001 Aug 10
Molecular species composition of rat liver phospholipids by ESI-MS/MS: the effect of chromatography.
2001 Dec
Albumin is the major plasma protein target of oxidant stress in uremia.
2001 Jul
Characterization of chemical interferences in the determination of unsaturated aldehydes using aromatic hydrazine reagents and liquid chromatography.
2001 Jun
Evaluation of media and derivatization chemistry for six aldehydes in a passive sampler.
2001 Jun 1
Oxidative damage to proteins and decrease of antioxidant capacity in patients with varicocele.
2001 Jun 1
Chronic ethanol consumption alters the glutathione/glutathione peroxidase-1 system and protein oxidation status in rat liver.
2001 May
Plasma ascorbic acid concentrations in a population of rhesus monkeys (Macaca mulatta).
2001 May
Determination of aldehydes in fish by high-performance liquid chromatography.
2001 May
Combination of vitamin C and rutin on neuropathy and lung damage of diabetes mellitus rats.
2002 Apr
The influence of Sacoglottis gabonensis stem bark extract and its isolate bergenin, Nigerian alcoholic beverage additives, on the metabolic and haematological side effects of 2,4-dinitrophenyl hydrazine-induced tissue damage.
2002 Dec
Location of abasic sites in oligodeoxynucleotides by tandem mass spectrometry and by a chemical cleavage initiated by an unusual reaction of the ODN with MALDI matrix.
2002 Dec
Determination of phosphonic acid breakdown products by high-performance liquid chromatography after derivatization.
2002 Jan 4
2-(exo-tricyclo[5.2.1.0(2,6)]deca-4,8-dien-3-endo-yl)acetaldehyde 2,4-dinitrophenylhydrazone.
2002 Jul
Formation of cyclopropanone during cytochrome P450-catalyzed N-dealkylation of a cyclopropylamine.
2002 Jul 17
Method for analysis of 4-hydroxy-2-(E)-nonenal with solid-phase microextraction.
2002 Jun
Increase in oxidative damage to lipids and proteins in skeletal muscle of uremic patients.
2002 Mar
Results from interlaboratory comparisons of aldehyde-2,4 dinitrophenylhydrazone analysis.
2002 Mar
HPLC-MS determination of the oxidation products of the reaction between alpha- and beta-pinene and OH radicals.
2002 Mar
Method optimization for the determination of carbonyl compounds in disinfected water by DNPH derivatization and LC-ESI-MS-MS.
2002 Mar
Identification of human urine stains by HPLC analysis of 17-ketosteroid conjugates.
2002 May
Detection of oxidative stress. Interest of GC-MS for malondialdehyde and formaldehyde monitoring.
2002 May
Identification of oxidized plasma proteins in Alzheimer's disease.
2002 May 24
Proteomic analysis of protein oxidation in Alzheimer's disease brain.
2002 Sep
Determination of patterns of biologically relevant aldehydes in exhaled breath condensate of healthy subjects by liquid chromatography/atmospheric chemical ionization tandem mass spectrometry.
2003
Primary oxidation products affect the quantification of formaldehyde in autoxidized fatty alcohol ethoxylates when using DNPH derivatization.
2003 Jan
Hypochlorite scavenging activity of hydroxycinnamic acids evaluated by a rapid microplate method based on the measurement of chloramines.
2003 Jul
Correlation between Helicobacter pylori infection and vitamin C levels in whole blood, plasma, and gastric juice, and the pH of gastric juice in Korean children.
2003 Jul
Benzaldehyde 2,4-dinitrophenylhydrazone.
2003 Mar
Protein carbonyl groups as biomarkers of oxidative stress.
2003 Mar
Quantitation of nitric oxide-derived nitrite from activated macrophages using microdialysis sampling.
2003 Nov 5
Automated method for determination of glutardialdehyde residues in flexible endoscopes after disinfection.
2003 Oct 5
Drying of linseed oil paints: the effects of substrate on the emission of aldehydes.
2003 Sep
A fast and accurate method to measure both oxidative stress and vitality in a single organ slice.
2003 Sep 1
Development of a compound-specific isotope analysis method for acetone via 2,4-dinitrophenylhydrazine derivatization.
2004
S-allylmercaptocysteine scavenges hydroxyl radical and singlet oxygen in vitro and attenuates gentamicin-induced oxidative and nitrosative stress and renal damage in vivo.
2004 Apr 30
Oxidative damage of biomolecules in mouse liver induced by morphine and protected by antioxidants.
2004 Aug
Determination of hexanal as indicator of the lipidic oxidation state in potato crisps using gas chromatography and high-performance liquid chromatography.
2004 Aug 13
Response of DNA, proteins and membrane bilayer in the digestive gland cells of freshwater mussel Unio tumidus to tannins exposure.
2004 Dec
Validated HPLC determination of 2-[(dimethylamino)methyl]cyclohexanone, an impurity in tramadol, using a precolumn derivatisation reaction with 2,4-dinitrophenylhydrazine.
2004 Jan 27
Study of the carbonyl products of terpene/OH radical reactions: detection of the 2,4-DNPH derivatives by HPLC-MS.
2004 Jun
Quantitative analysis of the flavonoids in raw propolis from northern Croatia.
2004 Mar
Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary Parkinsonism.
2004 Nov
Patents
Name Type Language
2,4-DINITROPHENYLHYDRAZINE HYDROCHLORIDE
Systematic Name English
HYDRAZINE, (2,4-DINITROPHENYL)-, MONOHYDROCHLORIDE
Systematic Name English
HYDRAZINE, (2,4-DINITROPHENYL)-, HYDROCHLORIDE (1:1)
Systematic Name English
2,4-DINITROPHENYLHYDRAZINIUM(1+) CHLORIDE
Common Name English
(2,4-DINITROPHENYL)HYDRAZINE HYDROCHLORIDE
Systematic Name English
Code System Code Type Description
FDA UNII
XG0EL78CX0
Created by admin on Sat Dec 16 12:21:48 GMT 2023 , Edited by admin on Sat Dec 16 12:21:48 GMT 2023
PRIMARY
ECHA (EC/EINECS)
259-888-5
Created by admin on Sat Dec 16 12:21:48 GMT 2023 , Edited by admin on Sat Dec 16 12:21:48 GMT 2023
PRIMARY
EPA CompTox
DTXSID40204505
Created by admin on Sat Dec 16 12:21:48 GMT 2023 , Edited by admin on Sat Dec 16 12:21:48 GMT 2023
PRIMARY
CAS
76195-86-3
Created by admin on Sat Dec 16 12:21:48 GMT 2023 , Edited by admin on Sat Dec 16 12:21:48 GMT 2023
NON-SPECIFIC STOICHIOMETRY
PUBCHEM
5463312
Created by admin on Sat Dec 16 12:21:48 GMT 2023 , Edited by admin on Sat Dec 16 12:21:48 GMT 2023
PRIMARY
CAS
55907-61-4
Created by admin on Sat Dec 16 12:21:48 GMT 2023 , Edited by admin on Sat Dec 16 12:21:48 GMT 2023
PRIMARY