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Details

Stereochemistry ACHIRAL
Molecular Formula C6H6N4O4
Molecular Weight 198.1362
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2,4-DINITROPHENYLHYDRAZINE

SMILES

NNC1=CC=C(C=C1[N+]([O-])=O)[N+]([O-])=O

InChI

InChIKey=HORQAOAYAYGIBM-UHFFFAOYSA-N
InChI=1S/C6H6N4O4/c7-8-5-2-1-4(9(11)12)3-6(5)10(13)14/h1-3,8H,7H2

HIDE SMILES / InChI

Molecular Formula C6H6N4O4
Molecular Weight 198.1362
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Inhibition of rat brain microsomal cytochrome P450-dependent dealkylation activities by an oxidative stress.
2001 Aug
The influence of Sacoglottis gabonensis stem bark extract and its isolate bergenin, Nigerian alcoholic beverage additives, on the metabolic and haematological side effects of 2,4-dinitrophenyl hydrazine-induced tissue damage.
2002 Dec
[Biological markers for Alzheimer disease].
2003
Determination of patterns of biologically relevant aldehydes in exhaled breath condensate of healthy subjects by liquid chromatography/atmospheric chemical ionization tandem mass spectrometry.
2003
Antioxidant properties of extracts from Alchornea laxiflora (Benth) Pax and Hoffman.
2003 Aug
Patterns of protein carbonylation following oxidative stress in wild-type and sigB Bacillus subtilis cells.
2003 Aug
Effect of DBP/DEHP in vegetable planted soil on the quality of capsicum fruit.
2003 Feb
Hypochlorite scavenging activity of hydroxycinnamic acids evaluated by a rapid microplate method based on the measurement of chloramines.
2003 Jul
Correlation between Helicobacter pylori infection and vitamin C levels in whole blood, plasma, and gastric juice, and the pH of gastric juice in Korean children.
2003 Jul
Automated coupling of capillary-HPLC to matrix-assisted laser desorption/ionization mass spectrometry for the analysis of small molecules utilizing a reactive matrix.
2003 Jul
Benzaldehyde 2,4-dinitrophenylhydrazone.
2003 Mar
A chain of edge-fused rings generated by the combination of an N-H...O hydrogen bond and an iodo-nitro interaction in 2-iodobenzaldehyde 4-nitrophenylhydrazone versus disordered and effectively isolated molecules in 2-iodobenzaldehyde 2,4-dinitrophenylhydrazone.
2003 Mar
Carbonyl stress induced by intravenous iron during haemodialysis.
2003 May
Isomerization of aldehyde-2,4-dinitrophenylhydrazone derivatives and validation of high-performance liquid chromatographic analysis.
2003 May 9
Aberrant profiles of native and oxidized glycoproteins in Alzheimer plasma.
2003 Nov
Quantitation of nitric oxide-derived nitrite from activated macrophages using microdialysis sampling.
2003 Nov 5
Solid-phase synthesis of lidocaine and procainamide analogues using backbone amide linker (BAL) anchoring.
2003 Nov-Dec
Artifact evidence in carbonyl compound sampling using the enclosure technique with cuvette system.
2003 Oct
Anti malondialdehyde-adduct immunological response as a possible marker of successful aging.
2003 Oct
Automated method for determination of glutardialdehyde residues in flexible endoscopes after disinfection.
2003 Oct 5
Influence of predialysis oxidative stress on peroxidation processes after renal transplantation.
2003 Sep
Drying of linseed oil paints: the effects of substrate on the emission of aldehydes.
2003 Sep
A fast and accurate method to measure both oxidative stress and vitality in a single organ slice.
2003 Sep 1
Measurement by reversed-phase high-performance liquid chromatography of malondialdehyde in normal human urine following derivatisation with 2,4-dinitrophenylhydrazine.
2003 Sep 5
Development of a compound-specific isotope analysis method for acetone via 2,4-dinitrophenylhydrazine derivatization.
2004
Inhibition by allyl sulfides and phenethyl isothiocyanate of methyl-n-pentylnitrosamine depentylation by rat esophageal microsomes, human and rat CYP2E1, and Rat CYP2A3.
2004
S-allylmercaptocysteine scavenges hydroxyl radical and singlet oxygen in vitro and attenuates gentamicin-induced oxidative and nitrosative stress and renal damage in vivo.
2004 Apr 30
Oxidative damage of biomolecules in mouse liver induced by morphine and protected by antioxidants.
2004 Aug
Intravenous iron administration induces oxidation of serum albumin in hemodialysis patients.
2004 Aug
Determination of hexanal as indicator of the lipidic oxidation state in potato crisps using gas chromatography and high-performance liquid chromatography.
2004 Aug 13
Response of DNA, proteins and membrane bilayer in the digestive gland cells of freshwater mussel Unio tumidus to tannins exposure.
2004 Dec
Determination of airborne carbonyls: comparison of a thermal desorption/GC method with the standard DNPH/HPLC method.
2004 Feb 1
Identification of 4-hydroxy-2-nonenal-modified peptides within unfractionated digests using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
2004 Feb 15
Gas chromatography-mass spectrometry of carbonyl compounds in cigarette mainstream smoke after derivatization with 2,4-dinitrophenylhydrazine.
2004 Feb 20
CYP3A4, CYP2C9 and CYP2B6 expression and ifosfamide turnover in breast cancer tissue microsomes.
2004 Feb 23
Hydrogen-bonded chains of rings in 3-iodobenzaldehyde 2,4-dinitrophenylhydrazone and 4-iodobenzaldehyde 2,4-dinitrophenylhydrazone, and a three-dimensional framework in 4-iodobenzaldehyde 4-nitrophenylhydrazone generated by the combination of N-H...O and C-H...O hydrogen bonds with iodo-nitro interactions.
2004 Jan
Validated HPLC determination of 2-[(dimethylamino)methyl]cyclohexanone, an impurity in tramadol, using a precolumn derivatisation reaction with 2,4-dinitrophenylhydrazine.
2004 Jan 27
Manufactured nanomaterials (fullerenes, C60) induce oxidative stress in the brain of juvenile largemouth bass.
2004 Jul
Methyl malondialdehyde is not suitable as an internal standard for malondialdehyde detection in urine after derivatisation with 2,4-dinitrophenylhydrazine.
2004 Jul 5
Study of the carbonyl products of terpene/OH radical reactions: detection of the 2,4-DNPH derivatives by HPLC-MS.
2004 Jun
Oxidative stress is associated with XIAP and Smac/DIABLO signaling pathways in mouse brains after transient focal cerebral ischemia.
2004 Jun
Determination of malondialdehyde by liquid chromatography as the 2,4-dinitrophenylhydrazone derivative: a marker for oxidative stress in cell cultures of human hepatoma HepG2.
2004 Jun 5
Quantitative analysis of the flavonoids in raw propolis from northern Croatia.
2004 Mar
Colorimetric monitoring of solid-phase aldehydes using 2,4-dinitrophenylhydrazine.
2004 Mar-Apr
Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary Parkinsonism.
2004 Nov
Simultaneous determination of C1-C4 carboxylic acids and aldehydes using 2,4-dinitrophenylhydrazine-impregnated silica gel and high-performance liquid chromatography.
2004 Oct 1
Assay of plasma semicarbazide-sensitive amine oxidase and determination of its endogenous substrate methylamine by liquid chromatography.
2004 Oct 25
Methionine sulphoxide reductase is an important antioxidant enzyme in the gastric pathogen Helicobacter pylori.
2004 Sep
[Exposure to formaldehyde during an anatomy dissecting course].
2004 Sep 1
Determination of lipid oxidation level in broiler meat by liquid chromatography.
2004 Sep-Oct
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 19:14:27 GMT 2023
Edited
by admin
on Fri Dec 15 19:14:27 GMT 2023
Record UNII
1N39KD7QPJ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
2,4-DINITROPHENYLHYDRAZINE
Systematic Name English
(2,4-DINITROPHENYL)HYDRAZINE
MI  
Systematic Name English
DINITROPHENYL)HYDRAZINE, (2,4-
Common Name English
NSC-5709
Code English
(2,4-DINITROPHENYL)HYDRAZINE [MI]
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID2059485
Created by admin on Fri Dec 15 19:14:27 GMT 2023 , Edited by admin on Fri Dec 15 19:14:27 GMT 2023
PRIMARY
CAS
119-26-6
Created by admin on Fri Dec 15 19:14:27 GMT 2023 , Edited by admin on Fri Dec 15 19:14:27 GMT 2023
PRIMARY
WIKIPEDIA
2,4-DINITROPHENYLHYDRAZINE
Created by admin on Fri Dec 15 19:14:27 GMT 2023 , Edited by admin on Fri Dec 15 19:14:27 GMT 2023
PRIMARY
ECHA (EC/EINECS)
204-309-3
Created by admin on Fri Dec 15 19:14:27 GMT 2023 , Edited by admin on Fri Dec 15 19:14:27 GMT 2023
PRIMARY
FDA UNII
1N39KD7QPJ
Created by admin on Fri Dec 15 19:14:27 GMT 2023 , Edited by admin on Fri Dec 15 19:14:27 GMT 2023
PRIMARY
NSC
5709
Created by admin on Fri Dec 15 19:14:27 GMT 2023 , Edited by admin on Fri Dec 15 19:14:27 GMT 2023
PRIMARY
MERCK INDEX
m4581
Created by admin on Fri Dec 15 19:14:27 GMT 2023 , Edited by admin on Fri Dec 15 19:14:27 GMT 2023
PRIMARY Merck Index
MESH
C004787
Created by admin on Fri Dec 15 19:14:27 GMT 2023 , Edited by admin on Fri Dec 15 19:14:27 GMT 2023
PRIMARY
PUBCHEM
3772977
Created by admin on Fri Dec 15 19:14:27 GMT 2023 , Edited by admin on Fri Dec 15 19:14:27 GMT 2023
PRIMARY
Related Record Type Details
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