Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H6N4O4 |
| Molecular Weight | 198.1362 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NNC1=CC=C(C=C1[N+]([O-])=O)[N+]([O-])=O
InChI
InChIKey=HORQAOAYAYGIBM-UHFFFAOYSA-N
InChI=1S/C6H6N4O4/c7-8-5-2-1-4(9(11)12)3-6(5)10(13)14/h1-3,8H,7H2
| Molecular Formula | C6H6N4O4 |
| Molecular Weight | 198.1362 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Response of DNA, proteins and membrane bilayer in the digestive gland cells of freshwater mussel Unio tumidus to tannins exposure. | 2004-12 |
|
| Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary Parkinsonism. | 2004-11 |
|
| Assay of plasma semicarbazide-sensitive amine oxidase and determination of its endogenous substrate methylamine by liquid chromatography. | 2004-10-25 |
|
| Determination of lipid oxidation level in broiler meat by liquid chromatography. | 2004-10-21 |
|
| Simultaneous determination of C1-C4 carboxylic acids and aldehydes using 2,4-dinitrophenylhydrazine-impregnated silica gel and high-performance liquid chromatography. | 2004-10-01 |
|
| [Exposure to formaldehyde during an anatomy dissecting course]. | 2004-09-01 |
|
| Methionine sulphoxide reductase is an important antioxidant enzyme in the gastric pathogen Helicobacter pylori. | 2004-09 |
|
| Determination of hexanal as indicator of the lipidic oxidation state in potato crisps using gas chromatography and high-performance liquid chromatography. | 2004-08-13 |
|
| Oxidative damage of biomolecules in mouse liver induced by morphine and protected by antioxidants. | 2004-08 |
|
| Intravenous iron administration induces oxidation of serum albumin in hemodialysis patients. | 2004-08 |
|
| Methyl malondialdehyde is not suitable as an internal standard for malondialdehyde detection in urine after derivatisation with 2,4-dinitrophenylhydrazine. | 2004-07-05 |
|
| Manufactured nanomaterials (fullerenes, C60) induce oxidative stress in the brain of juvenile largemouth bass. | 2004-07 |
|
| Determination of malondialdehyde by liquid chromatography as the 2,4-dinitrophenylhydrazone derivative: a marker for oxidative stress in cell cultures of human hepatoma HepG2. | 2004-06-05 |
|
| Study of the carbonyl products of terpene/OH radical reactions: detection of the 2,4-DNPH derivatives by HPLC-MS. | 2004-06 |
|
| Oxidative stress is associated with XIAP and Smac/DIABLO signaling pathways in mouse brains after transient focal cerebral ischemia. | 2004-06 |
|
| S-allylmercaptocysteine scavenges hydroxyl radical and singlet oxygen in vitro and attenuates gentamicin-induced oxidative and nitrosative stress and renal damage in vivo. | 2004-04-30 |
|
| Colorimetric monitoring of solid-phase aldehydes using 2,4-dinitrophenylhydrazine. | 2004-03-09 |
|
| Quantitative analysis of the flavonoids in raw propolis from northern Croatia. | 2004-03 |
|
| CYP3A4, CYP2C9 and CYP2B6 expression and ifosfamide turnover in breast cancer tissue microsomes. | 2004-02-23 |
|
| Gas chromatography-mass spectrometry of carbonyl compounds in cigarette mainstream smoke after derivatization with 2,4-dinitrophenylhydrazine. | 2004-02-20 |
|
| Identification of 4-hydroxy-2-nonenal-modified peptides within unfractionated digests using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. | 2004-02-15 |
|
| Determination of airborne carbonyls: comparison of a thermal desorption/GC method with the standard DNPH/HPLC method. | 2004-02-01 |
|
| Validated HPLC determination of 2-[(dimethylamino)methyl]cyclohexanone, an impurity in tramadol, using a precolumn derivatisation reaction with 2,4-dinitrophenylhydrazine. | 2004-01-27 |
|
| Hydrogen-bonded chains of rings in 3-iodobenzaldehyde 2,4-dinitrophenylhydrazone and 4-iodobenzaldehyde 2,4-dinitrophenylhydrazone, and a three-dimensional framework in 4-iodobenzaldehyde 4-nitrophenylhydrazone generated by the combination of N-H...O and C-H...O hydrogen bonds with iodo-nitro interactions. | 2004-01 |
|
| Development of a compound-specific isotope analysis method for acetone via 2,4-dinitrophenylhydrazine derivatization. | 2004 |
|
| Inhibition by allyl sulfides and phenethyl isothiocyanate of methyl-n-pentylnitrosamine depentylation by rat esophageal microsomes, human and rat CYP2E1, and Rat CYP2A3. | 2004 |
|
| Solid-phase synthesis of lidocaine and procainamide analogues using backbone amide linker (BAL) anchoring. | 2003-11-11 |
|
| Quantitation of nitric oxide-derived nitrite from activated macrophages using microdialysis sampling. | 2003-11-05 |
|
| Aberrant profiles of native and oxidized glycoproteins in Alzheimer plasma. | 2003-11 |
|
| Automated method for determination of glutardialdehyde residues in flexible endoscopes after disinfection. | 2003-10-05 |
|
| Artifact evidence in carbonyl compound sampling using the enclosure technique with cuvette system. | 2003-10 |
|
| Anti malondialdehyde-adduct immunological response as a possible marker of successful aging. | 2003-10 |
|
| Measurement by reversed-phase high-performance liquid chromatography of malondialdehyde in normal human urine following derivatisation with 2,4-dinitrophenylhydrazine. | 2003-09-05 |
|
| A fast and accurate method to measure both oxidative stress and vitality in a single organ slice. | 2003-09-01 |
|
| Influence of predialysis oxidative stress on peroxidation processes after renal transplantation. | 2003-09 |
|
| Drying of linseed oil paints: the effects of substrate on the emission of aldehydes. | 2003-09 |
|
| Antioxidant properties of extracts from Alchornea laxiflora (Benth) Pax and Hoffman. | 2003-08 |
|
| Patterns of protein carbonylation following oxidative stress in wild-type and sigB Bacillus subtilis cells. | 2003-08 |
|
| Hypochlorite scavenging activity of hydroxycinnamic acids evaluated by a rapid microplate method based on the measurement of chloramines. | 2003-07 |
|
| Correlation between Helicobacter pylori infection and vitamin C levels in whole blood, plasma, and gastric juice, and the pH of gastric juice in Korean children. | 2003-07 |
|
| Automated coupling of capillary-HPLC to matrix-assisted laser desorption/ionization mass spectrometry for the analysis of small molecules utilizing a reactive matrix. | 2003-07 |
|
| Isomerization of aldehyde-2,4-dinitrophenylhydrazone derivatives and validation of high-performance liquid chromatographic analysis. | 2003-05-09 |
|
| Carbonyl stress induced by intravenous iron during haemodialysis. | 2003-05 |
|
| Benzaldehyde 2,4-dinitrophenylhydrazone. | 2003-03 |
|
| A chain of edge-fused rings generated by the combination of an N-H...O hydrogen bond and an iodo-nitro interaction in 2-iodobenzaldehyde 4-nitrophenylhydrazone versus disordered and effectively isolated molecules in 2-iodobenzaldehyde 2,4-dinitrophenylhydrazone. | 2003-03 |
|
| Effect of DBP/DEHP in vegetable planted soil on the quality of capsicum fruit. | 2003-02 |
|
| [Biological markers for Alzheimer disease]. | 2003 |
|
| Determination of patterns of biologically relevant aldehydes in exhaled breath condensate of healthy subjects by liquid chromatography/atmospheric chemical ionization tandem mass spectrometry. | 2003 |
|
| The influence of Sacoglottis gabonensis stem bark extract and its isolate bergenin, Nigerian alcoholic beverage additives, on the metabolic and haematological side effects of 2,4-dinitrophenyl hydrazine-induced tissue damage. | 2002-12 |
|
| Inhibition of rat brain microsomal cytochrome P450-dependent dealkylation activities by an oxidative stress. | 2001-08 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:39:38 GMT 2025
by
admin
on
Mon Mar 31 19:39:38 GMT 2025
|
| Record UNII |
1N39KD7QPJ
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
DTXSID2059485
Created by
admin on Mon Mar 31 19:39:38 GMT 2025 , Edited by admin on Mon Mar 31 19:39:38 GMT 2025
|
PRIMARY | |||
|
119-26-6
Created by
admin on Mon Mar 31 19:39:38 GMT 2025 , Edited by admin on Mon Mar 31 19:39:38 GMT 2025
|
PRIMARY | |||
|
2,4-DINITROPHENYLHYDRAZINE
Created by
admin on Mon Mar 31 19:39:38 GMT 2025 , Edited by admin on Mon Mar 31 19:39:38 GMT 2025
|
PRIMARY | |||
|
204-309-3
Created by
admin on Mon Mar 31 19:39:38 GMT 2025 , Edited by admin on Mon Mar 31 19:39:38 GMT 2025
|
PRIMARY | |||
|
1N39KD7QPJ
Created by
admin on Mon Mar 31 19:39:38 GMT 2025 , Edited by admin on Mon Mar 31 19:39:38 GMT 2025
|
PRIMARY | |||
|
5709
Created by
admin on Mon Mar 31 19:39:38 GMT 2025 , Edited by admin on Mon Mar 31 19:39:38 GMT 2025
|
PRIMARY | |||
|
m4581
Created by
admin on Mon Mar 31 19:39:38 GMT 2025 , Edited by admin on Mon Mar 31 19:39:38 GMT 2025
|
PRIMARY | Merck Index | ||
|
C004787
Created by
admin on Mon Mar 31 19:39:38 GMT 2025 , Edited by admin on Mon Mar 31 19:39:38 GMT 2025
|
PRIMARY | |||
|
3772977
Created by
admin on Mon Mar 31 19:39:38 GMT 2025 , Edited by admin on Mon Mar 31 19:39:38 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
SALT/SOLVATE -> PARENT |
