Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C20H21NO4 |
| Molecular Weight | 339.385 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC2=C3[C@H](CC4=C(C=C5OCOC5=C4)C3=C1OC)N(C)CC2
InChI
InChIKey=WSVWKHTVFGTTKJ-AWEZNQCLSA-N
InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Affinity of aporphines for the human 5-HT2A receptor: insights from homology modeling and molecular docking studies. | 2010-08-01 |
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| Synthetic studies and pharmacological evaluations on the MDMA ('Ecstasy') antagonist nantenine. | 2010-01-15 |
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| Beta2-adrenoceptor-mediated tracheal relaxation induced by higenamine from Nandina domestica Thunberg. | 2009-10 |
|
| [Chemical constituents from Corydalis yanhusuo]. | 2009-08 |
|
| (+/-)-Nantenine analogs as antagonists at human 5-HT(2A) receptors: C1 and flexible congeners. | 2009-05-01 |
|
| The extract from Nandina domestica THUNBERG inhibits histamine- and serotonin-induced contraction in isolated guinea pig trachea. | 2007-11 |
|
| Nantenine: an antagonist of the behavioral and physiological effects of MDMA in mice. | 2004-05 |
|
| Acute cardiovascular effects of (+)-nantenine, an alkaloid isolated from Platycapnos spicata, in anaesthetised normotensive rats. | 2004-02 |
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| (+)-Nantenine isolated from Nandina domestica Thunb. inhibits adrenergic pressor responses in pithed rats. | 2003-09-05 |
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| Nantenine blocks muscle contraction and Ca2+ transient induced by noradrenaline and K+ in rat vas deferens. | 2003-05-30 |
|
| Pharmacological effects of (+)-nantenine, an alkaloid isolated from Platycapnos spicata, in several rat isolated tissues. | 2003-02 |
|
| Nantenine alkaloid presents anticonvulsant effect on two classical animal models. | 2003 |
|
| Suppressive effect of nantenine, isolated from Nandina domestica Thunberg, on the 5-hydroxy-L-tryptophan plus clorgyline-induced head-twitch response in mice. | 2002-04-19 |
|
| Structure-activity relationship on (+/-)-nantenine derivatives in antiserotonergic activities in rat aorta. | 2002-03 |
|
| Structure-activity relationship studies with (+/-)-nantenine derivatives for alpha1-adrenoceptor antagonist activity. | 2002-02-22 |
|
| Preliminary study of the vasorelaxant effects of (+)-nantenine, an alkaloid isolated from Platycapnos spicata, in rat aorta. | 2001-12 |
|
| In vitro dose dependent inverse effect of nantenine on synaptosomal membrane K+-p-NPPase activity. | 2001-03 |
Patents
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| Code System | Code | Type | Description | ||
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DTXSID70180343
Created by
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2565-01-7
Created by
admin on Mon Mar 31 22:20:27 GMT 2025 , Edited by admin on Mon Mar 31 22:20:27 GMT 2025
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197001
Created by
admin on Mon Mar 31 22:20:27 GMT 2025 , Edited by admin on Mon Mar 31 22:20:27 GMT 2025
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m4732
Created by
admin on Mon Mar 31 22:20:27 GMT 2025 , Edited by admin on Mon Mar 31 22:20:27 GMT 2025
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PRIMARY | Merck Index | ||
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Nantenine
Created by
admin on Mon Mar 31 22:20:27 GMT 2025 , Edited by admin on Mon Mar 31 22:20:27 GMT 2025
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XE0AU8C122
Created by
admin on Mon Mar 31 22:20:27 GMT 2025 , Edited by admin on Mon Mar 31 22:20:27 GMT 2025
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PRIMARY |
SUBSTANCE RECORD
