Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C20H21NO4 |
| Molecular Weight | 339.385 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]12CC3=C(C=C4OCOC4=C3)C5=C(OC)C(OC)=CC(CCN1C)=C25
InChI
InChIKey=WSVWKHTVFGTTKJ-AWEZNQCLSA-N
InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1
| Molecular Formula | C20H21NO4 |
| Molecular Weight | 339.385 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| (+)-Nantenine isolated from Nandina domestica Thunb. inhibits adrenergic pressor responses in pithed rats. | 2003 Sep 5 |
|
| Acute cardiovascular effects of (+)-nantenine, an alkaloid isolated from Platycapnos spicata, in anaesthetised normotensive rats. | 2004 Feb |
|
| The extract from Nandina domestica THUNBERG inhibits histamine- and serotonin-induced contraction in isolated guinea pig trachea. | 2007 Nov |
|
| (+/-)-Nantenine analogs as antagonists at human 5-HT(2A) receptors: C1 and flexible congeners. | 2009 May 1 |
|
| Beta2-adrenoceptor-mediated tracheal relaxation induced by higenamine from Nandina domestica Thunberg. | 2009 Oct |
|
| Affinity of aporphines for the human 5-HT2A receptor: insights from homology modeling and molecular docking studies. | 2010 Aug 1 |
|
| Synthetic studies and pharmacological evaluations on the MDMA ('Ecstasy') antagonist nantenine. | 2010 Jan 15 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 08:50:42 GMT 2023
by
admin
on
Sat Dec 16 08:50:42 GMT 2023
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| Record UNII |
XE0AU8C122
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| Record Status |
Validated (UNII)
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| Record Version |
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2565-01-7
Created by
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197001
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m4732
Created by
admin on Sat Dec 16 08:50:42 GMT 2023 , Edited by admin on Sat Dec 16 08:50:42 GMT 2023
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PRIMARY | Merck Index | ||
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Nantenine
Created by
admin on Sat Dec 16 08:50:42 GMT 2023 , Edited by admin on Sat Dec 16 08:50:42 GMT 2023
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XE0AU8C122
Created by
admin on Sat Dec 16 08:50:42 GMT 2023 , Edited by admin on Sat Dec 16 08:50:42 GMT 2023
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PRIMARY |