SKF-77434

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C19H21NO2
Molecular Weight	295.3755
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of SKF-77434

Structure Search

SMILES

OC1=CC2=C(C=C1O)C(CN(CC=C)CC2)C3=CC=CC=C3

InChI

InChIKey=QBUVZVXIRYFENV-UHFFFAOYSA-N

InChI=1S/C19H21NO2/c1-2-9-20-10-8-15-11-18(21)19(22)12-16(15)17(13-20)14-6-4-3-5-7-14/h2-7,11-12,17,21-22H,1,8-10,13H2

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Dopamine D1 receptor 101 Target ID: CHEMBL265 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1533424	Partial Agonist 290		19.7 nM [IC50]

PubMed

PubMed

Title	Date	PubMed
Differential activation of adenylate cyclase and receptor internalization by novel dopamine D1 receptor agonists.	2005 Oct	15985612

Patents

Patents

Name

Type

Language

SKF-77434

Common Name

English

(±)-SKF-77434

Code

English

1H-3-BENZAZEPINE-7,8-DIOL, 2,3,4,5-TETRAHYDRO-1-PHENYL-3-(2-PROPENYL)-

Systematic Name

English

1H-3-BENZAZEPINE-7,8-DIOL, 2,3,4,5-TETRAHYDRO-1-PHENYL-3-(2-PROPEN-1-YL)-

Systematic Name

English

J247.964H

Code

English

Code System Code Type Description

EPA CompTox

DTXSID3043817

Created by admin on Sat Dec 16 11:51:28 GMT 2023 , Edited by admin on Sat Dec 16 11:51:28 GMT 2023

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PUBCHEM

1241

Created by admin on Sat Dec 16 11:51:28 GMT 2023 , Edited by admin on Sat Dec 16 11:51:28 GMT 2023

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CHEBI

63988

Created by admin on Sat Dec 16 11:51:28 GMT 2023 , Edited by admin on Sat Dec 16 11:51:28 GMT 2023

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CAS

104422-04-0

Created by admin on Sat Dec 16 11:51:28 GMT 2023 , Edited by admin on Sat Dec 16 11:51:28 GMT 2023

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WIKIPEDIA

SKF-77,434

Created by admin on Sat Dec 16 11:51:28 GMT 2023 , Edited by admin on Sat Dec 16 11:51:28 GMT 2023

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FDA UNII

XA99M7XZR5

Created by admin on Sat Dec 16 11:51:28 GMT 2023 , Edited by admin on Sat Dec 16 11:51:28 GMT 2023

PRIMARY

ACTIVE MOIETY


					XA99M7XZR5

SKF-77434

SALT/SOLVATE (PARENT)


					1C4570NI42

SKF-77434 HYDROBROMIDE