SKF-77434 HYDROBROMIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C19H21NO2.BrH
Molecular Weight	376.287
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Br.OC1=CC2=C(C=C1O)C(CN(CC=C)CC2)C3=CC=CC=C3

InChI

InChIKey=JWQRAXTWDYUBFI-UHFFFAOYSA-N

InChI=1S/C19H21NO2.BrH/c1-2-9-20-10-8-15-11-18(21)19(22)12-16(15)17(13-20)14-6-4-3-5-7-14;/h2-7,11-12,17,21-22H,1,8-10,13H2;1H

HIDE SMILES / InChI

Molecular Formula	C19H21NO2
Molecular Weight	295.3755
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Molecular Formula	BrH
Molecular Weight	80.912
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Dopamine D1 receptor 101 Target ID: CHEMBL265 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1533424	Partial Agonist 290		19.7 nM [IC50]

PubMed

Title	Date	PubMed
Effects of chronic administration of the D1 receptor partial agonist SKF 77434 on cocaine self-administration in rhesus monkeys.	2002 Apr	11919663

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:39:39 GMT 2023` Edited by `admin` on `Sat Dec 16 08:39:39 GMT 2023`
Record UNII	1C4570NI42
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SKF-77434 HYDROBROMIDE

Common Name

English

1H-3-BENZAZEPINE-7,8-DIOL, 2,3,4,5-TETRAHYDRO-1-PHENYL-3-(2-PROPEN-1-YL)-, HYDROBROMIDE (1:1)

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID5042611

Created by admin on Sat Dec 16 08:39:39 GMT 2023 , Edited by admin on Sat Dec 16 08:39:39 GMT 2023

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PUBCHEM

11957703

Created by admin on Sat Dec 16 08:39:39 GMT 2023 , Edited by admin on Sat Dec 16 08:39:39 GMT 2023

PRIMARY

CAS

300561-58-4

Created by admin on Sat Dec 16 08:39:39 GMT 2023 , Edited by admin on Sat Dec 16 08:39:39 GMT 2023

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FDA UNII

1C4570NI42

Created by admin on Sat Dec 16 08:39:39 GMT 2023 , Edited by admin on Sat Dec 16 08:39:39 GMT 2023

PRIMARY

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SKF-77434

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