Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C19H20N4O2 |
| Molecular Weight | 336.3877 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1CCCC(C1)C(=O)N2C3=CC=CC=C3NC(=O)C4=CC=CN=C24
InChI
InChIKey=LPLNSPKKMWHFAU-UHFFFAOYSA-N
InChI=1S/C19H20N4O2/c1-22-11-5-6-13(12-22)19(25)23-16-9-3-2-8-15(16)21-18(24)14-7-4-10-20-17(14)23/h2-4,7-10,13H,5-6,11-12H2,1H3,(H,21,24)
Rispenzepine (DF 594) is a muscarinic receptor antagonist. Rispenzepine has high affinity for intestinal muscarinic receptors, with preferential action at M1 and M3 receptor subtypes. This drug shows potent inhibitory effects on intestinal motility. In guinea pigs, rispenzepine significantly increases acetylcholine release in the trachea. A phase II study to test efficacy in asthma patients has been discontinued.
Originator
Approval Year
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| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C29698
Created by
admin on Mon Mar 31 18:45:59 GMT 2025 , Edited by admin on Mon Mar 31 18:45:59 GMT 2025
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96449-05-7
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W99LLM73R7
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CHEMBL2106612
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SUB10334MIG
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DTXSID60869271
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100000080572
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129505
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6521
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C74175
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ACTIVE MOIETY
