BICLOTYMOL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H26Cl2O2
Molecular Weight	381.336
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)C1=CC(Cl)=C(C)C(CC2=C(C)C(Cl)=CC(C(C)C)=C2O)=C1O

InChI

InChIKey=HNOOXWDWUSLXOB-UHFFFAOYSA-N

InChI=1S/C21H26Cl2O2/c1-10(2)14-8-18(22)12(5)16(20(14)24)7-17-13(6)19(23)9-15(11(3)4)21(17)25/h8-11,24-25H,7H2,1-6H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/28925466

Biclotymol, a phenolic antiseptic has multiple actions: it has bacteriostatic, bactericidal, anti-inflammatory and analgesic activity. Biclotymol is recommended as a prompt, effective and safe first-line option for the treatment of sore throat.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
cell wall disassembly 1 Target ID: GO:0044277 Sources: https://www.ncbi.nlm.nih.gov/pubmed/28925466	Modulator 828

PubMed

Title	Date	PubMed

Sample Use Guides

In Vivo Use Guide

5-minute application of a 90% biclotymol-based mouthwash (Hexaspray, biclotymol 2.5%, Laboratoires Bouchara Recordati, France) reduced by 5-log the concentration of Pseudomonas aeruginosa strains (data on fle). Similar results were reported for Escherichia coli and Enterococcus strains.

Route of Administration: Irrigation

Name

Type

Language

BICLOTYMOL

Official Name

English

2,2'-METHYLENEBIS(6-CHLOROTHYMOLE)

Common Name

English

Biclotymol [WHO-DD]

Common Name

English

BICLOTYMOL [MART.]

Common Name

English

biclotymol [INN]

Common Name

English

HEXASPRAY

Brand Name

English

Classification Tree Code System Code

NCI_THESAURUS

C28394