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Details

Stereochemistry ACHIRAL
Molecular Formula C4H2O4.Ca
Molecular Weight 154.134
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of CALCIUM FUMARATE

SMILES

[Ca++].[O-]C(=O)\C=C\C([O-])=O

InChI

InChIKey=HDRTWMBOUSPQON-TYYBGVCCSA-L
InChI=1S/C4H4O4.Ca/c5-3(6)1-2-4(7)8;/h1-2H,(H,5,6)(H,7,8);/q;+2/p-2/b2-1+;

HIDE SMILES / InChI

Description

Calcium Fumarate is a calcium salt of fumaric acid, it can be used as a food supplement. Calcium Fumarate may be used to treat conditions caused by low Calcium levels such as bone loss (osteoporosis), weak bones (osteomalacia/rickets), decreased activity of the parathyroid gland (hypoparathyroidism), and a certain muscle disease (latent tetany). It may also be used in certain patients to make sure they are getting enough Calcium (e.g., women who are pregnant, nursing, or postmenopausal, people taking certain medications such as phenytoin, phenobarbital, or prednisone). Calcium Fumarate is classified by the FDA as a dietary and nutritional additive (21CFR§172.350) and has been used for many years.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Calcium Fumarate

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
According to the treatment schedule, after a 12 hours overnight fast, each subject was given tablets containing 675mg calcium in total either in the form of calcium gluconate or calcium fumarate orally with a glass of water. Standard breakfast was served after the 4th hour.
Route of Administration: Oral
In Vitro Use Guide
Unknown