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Phosphopantothenic acid is an amidoalkyl phosphate that is the 4-phosphate derivative of (R)-pantothenic acid. Phosphopantothenic acid is not permeable to cell membranes due to its anionic character, consistent with the observation that systemic administration of Phosphopantothenic acid does not restore CoA levels in cellular and mouse models

Approval Year

PubMed

PubMed

TitleDatePubMed
Chemo- and regioselective peptide cyclization triggered by the N-terminal fatty acid chain length: the recombinant cyclase of the calcium-dependent antibiotic from Streptomyces coelicolor.
2004 Mar 16
Mycobacterium tuberculosis pantothenate kinase: possible changes in location of ligands during enzyme action.
2009 Apr
Kinetic characterization of human phosphopantothenoylcysteine synthetase.
2009 Dec
Characterization and kinetics of phosphopantothenoylcysteine synthetase from Enterococcus faecalis.
2009 Mar 31
Selective inhibitors of bacterial phosphopantothenoylcysteine synthetase.
2009 Nov 18
Kinetic and inhibition studies of dihydroxybenzoate-AMP ligase from Escherichia coli.
2010 May 4
Patents
Name Type Language
FOSMETPANTOTENATE
INN   USAN  
USAN   INN  
Official Name English
FOSMETPANTOTENATE [USAN]
Common Name English
DIMETHYL 4-AMBO-(2S,8R)-8-HYDROXY-2,7,7-TRIMETHYL-4,9-DIOXO-4-PHENOXY-5-OXA-3,10-DIAZA-4.LAMBDA.5-PHOSPHATRIDECANEDIOATE
Systematic Name English
Fosmetpantotenate [WHO-DD]
Common Name English
RE-024
Code English
5-OXA-3,10-DIAZA-4-PHOSPHATRIDECANEDIOIC ACID, 8-HYDROXY-2,7,7-TRIMETHYL-9-OXO-4-PHENOXY-, 1,13-DIMETHYL ESTER, 4-OXIDE, (2S,8R)-
Systematic Name English
fosmetpantotenate [INN]
Common Name English
Classification Tree Code System Code
EU-Orphan Drug EU/3/16/1612
Created by admin on Sat Dec 16 12:52:09 GMT 2023 , Edited by admin on Sat Dec 16 12:52:09 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C170010
Created by admin on Sat Dec 16 12:52:09 GMT 2023 , Edited by admin on Sat Dec 16 12:52:09 GMT 2023
PRIMARY
INN
10531
Created by admin on Sat Dec 16 12:52:09 GMT 2023 , Edited by admin on Sat Dec 16 12:52:09 GMT 2023
PRIMARY
USAN
DE-51
Created by admin on Sat Dec 16 12:52:09 GMT 2023 , Edited by admin on Sat Dec 16 12:52:09 GMT 2023
PRIMARY
FDA UNII
VA101M0K2F
Created by admin on Sat Dec 16 12:52:09 GMT 2023 , Edited by admin on Sat Dec 16 12:52:09 GMT 2023
PRIMARY
PUBCHEM
71811909
Created by admin on Sat Dec 16 12:52:09 GMT 2023 , Edited by admin on Sat Dec 16 12:52:09 GMT 2023
PRIMARY
CAS
1858268-66-2
Created by admin on Sat Dec 16 12:52:09 GMT 2023 , Edited by admin on Sat Dec 16 12:52:09 GMT 2023
PRIMARY
All of the following components must be present:
Definition References